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All-In

Industry veterans Chamath Palihapitiya, Jason Calacanis, David Sacks, and David Friedberg cover economics, technology, politics, society, and poker.

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All-InEN · 51 min

Daniel Ek: Life After Spotify, Broken Healthcare Incentives, Catching Disease Early & AI's Potential

Daniel Ek

Spotify passed 700 million active users and 300 million premium subscribers; Daniel Ek became executive chairman January 1 and returned to building.Neko's $499 unit-economic-positive visit combines 53 blood markers, 6,000 images and clinician review in roughly an hour.Over 100,000 scans found serious, previously undiagnosed conditions in roughly 1% of members; population outcomes and budget effects remain unresolved.

All-InEN · 94 min

Anthropic IPO at Risk, Meta’s Muse Pop, Token Prices Fall, Open Source Gains Share, Alignment Fails

Chamath PalihapitiyaJason CalacanisDavid SacksDavid Friedberg

Open-source token usage flipped from 20% to 80% in 12 weeks; if more than 60–70% of frontier tokens are replaceable, Anthropic’s S-1 revenue must be discounted.Meta’s free Muse hit #1 in the App Store with 3M downloads in roughly 10 days, challenging the App Store’s 30% rev-share as agents make services headless.Converging models push OpenAI and Anthropic toward higher-value applications, while their six-to-12-month frontier lead remains the central risk.

All-InEN · 26 min

Luca Ferrari, Bending Spoons CEO: The $40K Start, Buying Product-Market Fit & Beating Private Equity

Luca Ferrari

Bending Spoons converts acquired product-market fit into a repeatable model, using 50+ proprietary tools and an approximately 800-person shared talent base to replace technology foundations.Historically consistent unlevered returns above 25% and debt costing about 9%, fully hedged and maturing in 2031, support the model, while limited customer synergies, competition and replication risk remain watchpoints.

All-InEN · 24 min

Adam Foroughi, Applovin CEO: Surviving a 92% Drawdown, Ads as ML 1.0 & the $50B Game Ad Market

Adam Foroughi

AppLovin is extending a roughly $50B mobile-gaming ad market, with platform ad spend growing from $11B to about $20B, into e-commerce discovery.Its April 2023 deep-learning model improved advertiser performance and enabled scaling, while roughly $6B in buybacks retired 20–25% of shares after a 92% drawdown.Discovery may expand activity beyond Google Search, but stated 84% EBITDA margins depend on differentiated data, complexity and scale.

All-InEN · 44 min

Meta's Dina Powell McCormick: The Case for Data Centers, Backlash, AI Job Boom & Meta’s Future

Dina Powell McCormick

Meta’s multibillion-dollar Richland Parish project lifted sales-tax growth from 5–10% to a 260% peak and certified employees’ checks from $10,000 to $50,000.Louisiana shifts generation, grid resilience, upgrades and storm costs to Meta; the Academy produced 250 graduates and 90% retention from 40,000 applicants, while Google and BlackRock support scaling amid backlash and Cotton and Warner’s adversary theory.

All-InEN · 18 min

Brad Gerstner: No AI Bubble, Semis Eat the Nasdaq & AI's Take Off Problem

Brad Gerstner

Gerstner argues the rally is earnings-driven, even as semiconductor concentration accounts for 70% of Nasdaq’s return.The AI buildout still depends on lab revenue scaling, while rates, power constraints, regulation and a delayed Anthropic IPO remain key risks.

All-InEN · 37 min

Satya Nadella on the AI Doomer Slowdown, Microsoft’s Master Plan & Who Wins AI

Satya Nadella

Persistent AI agents create a new insider-risk category: even mundane enterprise tasks could trigger reward hacking or falsified books.Behavioral monitoring, full auditability, and causal or semantic verification are the proposed response, while cheaper models shift margin toward applications and middleware.Microsoft’s “use all but be independent of all” strategy makes interoperability an adoption catalyst, but 7–8% broad-based GDP growth and social license remain tests.

All-InEN · 64 min

Elon Musk & Gwynne Shotwell on AI Risks and Peer Review, Starship, Terafab, SpaceX/Tesla Merger

Chamath PalihapitiyaJason CalacanisDavid SacksDavid FriedbergGwynne ShotwellElon Musk

Cross-lab AI peer review would give competitors pre-release API access to run logged safety harnesses, making distillation visible and raising reputational and product-liability stakes.Compute rental has become SpaceX’s “heck of a business,” with no drop in demand, while Starlink penetration remains 1.5–2%.Terafab and Starship’s flight 15 tower-catch attempt are milestones amid Taiwan supply risk and infrastructure constraints.

All-InEN · 47 min

Jensen Huang: The Doomer Hoax, Superintelligence is Here, and The Future of AI (ft. President Trump)

Jensen HuangPresident Trump

Jensen Huang cites failed forecasts on radiology, AI-generated code and entry-level jobs to challenge doomsday narratives, while arguing that AI incidents so far call for root-cause engineering and independent evaluation rather than sweeping regulation.With 80% of AI-native companies receiving $400 billion in recent venture funding using open models, NVIDIA is building infrastructure bottlenecks as Jensen predicts China will reach advanced lithography by 2030, leaving commercialization, lab controls and data-center execution to monitor.

All-InEN · 96 min

AI Kills Everybody or Doomer Psyop? OpenAI’s Math Breakthrough, Nike’s $200B Collapse

Chamath PalihapitiyaJason CalacanisDavid SacksDavid Friedberg

Anthropic’s IPO faces a disclosure test after Evan Hubinger endorsed a greater-than-10% extinction probability, despite Polymarket’s 88% odds.Sacks argues rapid amplification may reflect a coordinated campaign targeting open-source weights, though that remains his interpretation.OpenAI’s Navier–Stokes result shows brute-force leverage, while data-leakage risks favor sovereign deployment and Nike’s 80% decline underscores a product, channel, and brand reset.