All-In

Jared Isaacman

NASA is shifting capital from consensus-driven programs toward explicit national objectives, targeting Artemis 3 in summer 2027 and Artemis 4 in 2028.Repeated lunar missions could create demand for landers, rovers, and resource experiments, while public funding concentrates on fission power and nuclear-electric propulsion.SR1 Freedom’s 2028 target, uncertain lunar returns, and China’s ambitions make execution and launch capacity key watchpoints.

Jason Calacanis × Dino Mavrookas × Vibhav Altekar

Corsair’s rescue of two U.S. pilots in the Strait of Hormuz moved maritime autonomy from demonstration to operational trust, while Saronic’s 230-to-1 China-U.S. shipbuilding comparison frames industrial capacity as the central strategic gap.Its Marauder thesis targets payload economics through lower-cost, fixed-price autonomous vessels, with Brownsville and Louisiana yards adding scale; production, authorization thresholds, and the eventual manned-unmanned mix remain key variables.

Péter Fankhauser × Bernt Børnich × Amanda McMaster × Jonathan Hurst

Industrial robotics’ first validated wedge is data, not labor replacement: ANYmal and Spot can support roughly $100,000-$300,000 prices when avoided downtime or leaks protect losses measured in hundreds of thousands per hour.The $1-an-hour worker remains a scale end-state requiring $20,000-$40,000 hardware and 40,000 hours, while 1X’s handful of $500-per-month NEOs in 2026 will test autonomy, safety, and trust against Chinese hardware.

David Friedberg × Shyam Sankar × Trae Stephens

US military power is increasingly constrained by factory capacity, with Ukraine consuming “10 years of production in 10 weeks,” a 10,000-to-one drone gap, and a 223x shipbuilding disadvantage versus China.Anduril’s five-million-square-foot Arsenal-1 is designed as a modular manufacturing platform for attritable systems, addressing the economics of replacing $2 million interceptors with $20,000 drones.The high-low mix may shift massively over five to 10 years, but Stephens estimates roughly 18 months even with unlimited cash to establish a sustainable industrial base.

Travis Kalanick × Michael Dell

Atoms is extending Kalanick’s physical-computing architecture from food into mining automation through its near-closing Pronto acquisition, targeting more productive, safer, and potentially remote mines.Dell’s AI-infrastructure revenue is scaling toward $50 billion amid excess demand, while enterprise adoption and edge inference remain constrained by re-architecture, leadership, identity, and controls.

Elon Musk × Chamath Palihapitiya × Jason Calacanis × David Sacks × David Friedberg

Grok is moving X toward semantic ranking and search across text, images, and video, initially processing the top 10 million of roughly 100 million daily posts.Grokipedia’s broader, maximally truth-seeking corpus remains unproven amid factual errors, while Tesla’s Cybercab, Optimus, and inference ambitions depend on safety gates and Musk retaining roughly 25% voting influence.

Chamath Palihapitiya × Jason Calacanis × David Sacks × David Friedberg

California’s proposed one-time 5% levy on the full net worth of residents above $1 billion is legally shaky but politically potent, with capital flight the immediate risk before adjudication.The AWS outage gives Microsoft, Google Cloud and possibly Oracle a sales weapon as their 26%, 32% and possibly 40% growth outpaces AWS’s 17%.Amazon’s 75% warehouse-automation ambition could hold headcount flat while volume doubles, but the investment hinge is whether general-purpose robots break beyond today’s narrow machines.

Cathie Wood

Wood says five converging platforms—robotics, energy storage, AI, blockchain and multiomic sequencing—could lift real GDP growth toward “7% plus,” aided by Trump’s tax package.Robotaxis may monetize first, but sequencing, AI and CRISPR make healthcare AI her “most inefficiently priced” opportunity.ARK’s official Bitcoin bull case is $1.5 million, versus $3.8 million from portfolio optimization; Tesla’s $2,600 target and disruption’s rerating depend on execution.

David Friedberg × Cleo Abram × Alex Filippenko × Keller Rinaudo Cliffton

Cleo Abram’s six-million-subscriber Huge If True shows optimistic, technically serious creator media can scale globally, with sponsors funding ambitious work and streamers potentially extending validated YouTube IP.Webb is revealing unexpectedly early galaxies while Zipline demonstrates autonomous delivery at commercial scale, but US science cuts threaten the talent needed to analyze extraordinary data and expand critical infrastructure.

Dara Khosrowshahi

Uber’s autonomy strategy is to be a demand platform for more than 20 partners, subject to safety and economics.Khosrowshahi wants AVs to be “multiple times safer than a human being,” which he says is achievable; he also argues autonomy could eventually save millions of lives, lower mobility costs and expand the on-demand market.Falling…