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1000x · · 56 分钟

心理、价值与数据:Santiago Santos 如何穿越市场

Avi FelmanJonah Van BourgSantiago Santos

YouTube
TL;DR
  • Santos 正在逐步收束 Inversion 的加密投资主线。 在筛选了20+个行业、寻找稳定币可能重塑的生意后,他致信投资人,承认“以加密为筛选条件,让我们评估了一些比我愿意持有的企业更脆弱的公司”,并主动邀请反驳:“我宁愿现在就被证明是错的。”公司仍会继续投资,但转为寻找“技术只是旁支变量”的好生意——技术可以增益,但不应成为买入理由。
  • 跨境汇款的“尸检”最能说明问题。 尽管墨西哥家庭每笔汇款损失5-6%曾是他最初的加密顿悟,他最终发现 Remitly 和 Wise “赚不到钱”,也没有定价权;真正“打破了让世界两端同时获得资金这一赚钱物理定律”的,是代理商和履约合作方。他与汇款公司及加密创始人交叉交流后的结论是:“我们无法让这门生意变得更高效。”
  • 新的猎场是乏味、受监管驱动的现金流。 关键电力维护就是一例:医院管理者如果不检查发电机,“可能会坐牢”;收入来自合同,穿越周期,地域分散市场,紧急服务还能按3-4倍费率收费——“像软件,但更好”,再叠加AI在调度和报告上的利润率提升。另一类机会,是那些老板即将退休、却没有继承安排的企业。
  • 他的激励机制设计是差异化所在。 Inversion 采用控股公司而非基金结构,因为承诺资本会让人变得“急于出手”;他也不收2%管理费,因为“无论你如何面对镜子里的自己”,激励都会改变你——一只基金从2000万美元做到20亿美元,“你会越来越不像投资者,越来越像资产管理人”。团队只有3个人,募资2650万美元,大部分尚未花出;“除了判断,我们会把一切都自动化。”
  • 关于加密本身,他的判断是:“加密不会失败”(“crypto doesn't fail”)。 他可以“同时热爱这项技术,又极度看空估值”。无论 Bitcoin 价格如何,稳定币美元通道仍是杀手级应用;memecoin 是可负担性危机中的彩票,而监管借口消失后,行业必须自律——他以 token transparency act 为例。
  • AI交易呈杠铃结构。 一端持有算力、监管和“不会消失”的能源,另一端持有不可替代的人类体验——世界杯和 Wimbledon 票价达到15,000,老爷车胜过超级跑车。主持人最具体的判断是做多拥有专有数据的制药公司:历史上第一次出现了一个“科学家”——主持人称其为“Fable 5”——能同时覆盖神经科学、微生物组、睡眠和认知等领域;与被“学术黑帮”束缚的学界不同,AI“不在乎”维护旧理论。
  • 你是想赚钱,还是想证明自己正确? “赚钱,就是在共识形成前发现真相。”聪明人往往会扭曲世界来迎合自己的论点;Stan Druckenmiller 可能在一次会议上说“做多 Nvidia”,现场一片失望,但这恰恰体现了一个没有身份危机的人应有的状态:“我是投资者,只是恰好投资加密资产。”
摘要 · 为研究而整理的核心内容

1. 他刻意消除了口音——对所有劣势都用同一套方法处理

  • Santos 出生在墨西哥,却经常被当成美国人。成长过程中,他有意识地抹掉自己的口音:录下自己的声音,研究别人说话的方式。背后的逻辑是:“如果你正坐在某人对面……你就要消除信息传递中的任何损耗”,因为“人们有意无意都会评判你”。他说得更直接:“任何人都能把口音练好——我不想这么说,但有口音某种程度上就是懒。”主持人给他的标签是:主观能动性极强。
  • 他的父母给了他教育和旅行,而不是金钱。一个想去 Harvard 暑期学校的中学生,必须“去投资委员会答辩”。他从中得出的育儿结论是,孩子需要“时间、爱和支持系统,而不是钱”——需要确信“自己摔倒时会有一张网接住”。他把自己所有的成功都归因于那个相信一切皆有可能的单一时刻。
  • 当被问到一生中承担过的最大风险时,他想到的不是一笔交易,而是在 quinceañera 上邀请一个女孩跳舞。相比之下,押注 Bitcoin “相对于那种汗水和焦虑,简直像在公园里散步”——而“害怕被拒绝,可能是释放潜能时最大的瓶颈”。

2. 加密的起源:摩擦、汇款与数字化美元

  • 他的投资方法始于日常生活中的不适:“在你的日常互动中……观察哪里存在摩擦。”最早影响他的案例是,汇款是墨西哥家庭第一或第二大收入来源,而他们“每次都会被狠狠宰一笔……从美国把钱汇过去,至少损失5-6%”。
  • Bitcoin 带给他的顿悟,是跨境资金可以“更快、更好、更便宜”地流动,如今这一逻辑主要通过稳定币实现。“人们想要美元,一直以来都想要美元——那就给他们美元,尤其是数字形式的美元。”无论 Bitcoin 价格如何,这都是杀手级应用;“其他一切都还有待观察”。
  • 他进入这个行业的路径始于创伤:“随便找一个创始人聊聊,人人都有创伤。”他的二姐生病后,他做了2年投行、又在成长型股权基金工作2年,开始思考人生还能有什么可能。24岁时他进入加密领域,在旧金山一些不知名论坛上发现了“最聪明的那批人”,而当他告诉母亲自己的决定时,母亲“当场哭了出来”。

3. Inversion 的信:以加密为筛选条件,才是错误

  • 本期节目的新闻是,Santos 昨天给股东发了一封信,承认经过20+个行业的研究后,“我们还没有找到一个行业”。他在信中坦言:“我的错误在于,以加密为筛选条件,让我们评估了一些比我愿意持有的企业更脆弱的公司。”
  • 汇款业务的深挖支撑了这一论点:一家大型上市汇款公司认为稳定币会重塑其业务,于是他访谈了同业代表样本,以及正在搭建跨境支付通道的加密创始人。结果是,Remitly 和 Wise “赚不到钱”,单位经济性很差,监管覆盖面又大,而汇款公司没有定价权;真正“打破了让世界两端同时获得资金这一赚钱物理定律”的,是代理商和履约合作方。结论是:“我们无法让这门生意变得更高效。”
  • 他很谨慎地限定了结论范围:技术是真实存在的,而加密原生公司——Binance、Tether、交易所,以及很可能还有 Hyperliquid——都是“出色得惊人”的生意。但对于传统外汇、信贷和资产代币化业务,转型带来的收益从未“与承担的风险相称”;这类扭转需要“非常充足的安全边际”,而他始终没有找到。最后,他邀请市场反驳:“我宁愿现在就被证明是错的。”

4. 转向:技术只是旁支,先买生意

  • 他希望外界记住的一句话是:“我的错误在于,以为技术是买入一门生意的核心理由。它是正交项——技术可以增益,但你仍然必须买下一门好生意。”筛选标准是,无论市场环境如何都能产生有意义的现金流,同时受扰动风险较低——“如果找不到,就不要投资,买基准指数。”
  • 他给出的典型案例是关键电力维护:每家医院、学校和 hyperscaler 都受联邦法规要求,必须维护备用发电机;不做检查的管理者“可能会坐牢”。无论最新型号如何更新,收入都来自合同且持续产生;市场按地域分散,劳动力短缺,紧急服务还能按“正常费率的3、4倍”收费。“像软件,但更好”——AI可以进一步优化路线、排班和客户报告,成为利润率提升的催化剂。
  • 交易供给端的驱动力来自人口结构:德国、日本和美国有一批老板即将退休、却“没有继承安排”的企业。他重点看美国,“因为那里有法治”。模板仍然是 Warren 和 Charlie:“Warren 和 Charlie 的聪明之处,在于他们找到真正优秀的经营者,把钱交给他们,然后让资本持续复利。”

5. 激励机制:控股公司、不收2%,以及基金规模的心理学

  • Inversion 采用控股公司而不是基金,“背后有非常明确的原因”:承诺资本加上不断倒计时,会让人变得“急于出手”;而在研究了大量行业之后,如果最终选择放弃,沉没成本带来的压力会让“放弃投资”变得令人沮丧。他给自己的约束是:“我唯一、也是首要的任务,就是保护股东资本。”
  • 当被追问,如果收取2%管理费、不部署资本会不会更难受时,他的回答异常坦率:“当然……你不可能照着镜子说,自己的激励不会改变。那是在自欺欺人。”如果把他管理的基金从2000万美元扩大到20亿美元,“我的心理会改变……你会越来越不像投资者,越来越像资产管理人”。他特别提到 Benchmark 多年来一直把基金规模维持在3亿至4亿美元。
  • 规模控制是有意为之:募资2650万美元,实际花出的钱很少,团队只有3个人;他还提醒,Constellation 起步时只有2500万美元,Berkshire 也从小额资本做起。内部规则是:“除了判断,我们会把一切都自动化。”

6. “加密不会失败”——但行业必须照照镜子

  • 他的立场划分得很清楚:“我可以同时热爱这项技术,又极度看空估值。”当被问到加密行业的激励问题是否比其他行业更严重时,他回答是否定的——“只是伤害更大,因为这是一个拥有非常高原则性价值观的行业,而它又把这些价值观押在了自己身上。”
  • 他对 memecoin 的分析是社会学判断,而非道德审判:“熊市里人们会买更多彩票。”一方面是可负担性危机,另一方面是加密行业“打开了闸门,让原本无法接触投资产品的人也能参与”。他对此基本持放任态度,但也指出其中的矛盾:一些公司公开鼓吹现实世界资产,却把资源优先投向 memecoin。
  • 监管借口的时代已经结束:“很长时间里,我们都把问题归咎于监管者……现在这个借口基本消失了。”行业完全可以自律,他以 token transparency act 为一个正面例子;而当实际行为与自身宣扬的原则不一致时,“我们没有被认真对待,也就不奇怪了”。

7. 追寻真相胜过耍聪明——身份认同才是敌人

  • 他最大的投资错误,来自“试图用聪明的方式赚钱……你想证明自己聪明,想获得验证”。真正的测试是:“你是想赚钱,还是想证明自己正确?”因为“赚钱,就是在共识形成前发现真相”,而聪明人会“扭曲世界观,让它符合自己的思维方式”。
  • 他推测那个典型人物可能是 Stan Druckenmiller:在一次会议上——他记得可能是 Collison 兄弟主办的,或者类似场合——有人问他意见,他说“做多 Nvidia”。现场反应是:“真的?这就是你能给出的最好建议?”但结果相当不错。Santos 欣赏的是,他“对改变自己的想法感到极度自在”,也没有陷入“自己究竟是哪类投资者”的身份危机。他对自己的表述是:“我是投资者,只是恰好投资加密资产。”加密行业迫使他“同时成为一个高频交易者和风险投资人”——这是一次完整意义上的投资教育。
  • 他对 Inversion 的定位同样是追寻真相,而不是推销故事:“我想在其他人之前知道这个市场到底有多大”——是1万亿美元、10万亿美元,还是几亿美元——“然后做出那笔交易”。一位前老板听完后的回应,据他转述是:“你[__]。”
  • 这也适用于 LP:值得记住的是,“一些最优秀的募资人极其聪明……你必须提防那些听起来不可思议、但实际上不会投资的人。”他提到那本讲“被遗忘的亿万富翁”的书,其中一人曾是 Long-Term Capital Management 的管理者;也提到那些买入 Goldman SPV 的信托基金继承人——他们这么做,只是因为觉得这能让自己与众不同。

8. AI杠铃:押注两端,以及不可替代的人类体验

  • 他对“聪明人”观点的总结是:软件投资人说“软件已经过时了,软件就是商品”,服务更重要,硬件回来了。对应的投资组合是杠铃结构:“你应该投资两端的极致。”一端是 AI 基础设施——算力、监管和“不会消失”的能源;另一端是人类体验:世界杯和 Wimbledon 的票价达到15,000,“人们渴望回到线下”,老爷车胜过未来派超级跑车——“怀旧因素会变得更有价值”。
  • 主持人最尖锐的行业判断是:“我非常看多那些拥有大量数据的制药公司。”历史上第一次,一个实体可以“在不同数据集之间建立关系”,并拥有覆盖神经科学、微生物组、睡眠和认知的深层领域知识——“过去从来没有过这样一个科学家”,主持人将其称为“Fable 5”。学界做不到这一点,因为“学术界的黑帮比任何其他黑帮都严重”:一个60岁的人,如果自己一生坚持的衰老理论被推翻,绝不会站出来说“我错了”。但 AI “不在乎这些,它能突破这一层障碍”。
  • 他讲述的一个故事,承载着自己的乐观判断:一位澳大利亚人,家里的狗生病了,自己只懂一些生物学知识,却不断迭代,最终做出了 mRNA 疫苗;他顶住监管机构“你不是专家”的质疑,说服实验室完成生产——“那条狗已经没有癌症了。这个人会创办一家10亿美元级的制药公司……如果你看了这个故事还不受鼓舞,那我也没什么好说的。”
  • 他唯一的提醒是:“幻觉风险是真实存在的。”模型权重,以及“正在被提供的信息”都值得关注。超连接状态会让人“以为自己掌握了信息,但事实离真相还很远……这意味着市场会更加低效”。

9. 尖峰型胜过全面型——这是通才的时代

  • 本期最有代表性的段落,是他对自己母亲的回应:“她说,‘你需要变得更全面。’我说,这可能是我这辈子听过最扯的[__]……那就是平庸,字面意义上就是钟形曲线。”教育会“把最有尖峰特征的人也磨平”;他曾做过 SAT 家教,坚持认为刷题拿高分“不会让你成为一个从第一性原理出发思考的人”。
  • 在他的叙述中,尖峰能力是后天形成的,而不是与生俱来:“尖峰型的人之所以变得尖峰,就像你把口音练好一样。”而且人永远可以重塑自己:“你没有义务继续成为2分钟前的那个人。”
  • 所以现在正是这个时代:“专家被高估了。”带着适度妄想的局外人推动创新——Musk 不是航空航天工程师,青霉素也是偶然发现的;而 AI 正在压缩从脑中的想法到实际产品之间、发生在流水线上的“损耗”。他提到“claw code”(可能指 Claude Code)。他自己的状态是:“我过去6个月学到的东西,比以前多得多……这就像一场文艺复兴。这是我人生中最令人兴奋的时期。”
Santiago Santos

This is an issue I had with my parents, with my mom, and I love her. But she was like, “You need to be more well-rounded.” I’m like, “That’s the biggest load of bullshit I’ve ever heard in my life. I don’t want to be well-rounded. That’s mediocre.”

1. The Kid From Mexico Who Erased His Own Accent

Jonah Van Bourg

All right, guys. I have a very special guest here for you today: Santiago Santos. Thank you so much for joining us at the Selini Summit. We’ve got a great room that they’ve set us up with right next to the conference venue.

For those of you who aren’t in the know, this is a very special conference. Only the best people are here, and Santiago is one of the best of the best. Thank you for joining us.

Santiago Santos

Thank you, man. You’re fluffing me up. An in-person podcast hits differently.

Jonah Van Bourg

It’s kind of funny. You guys obviously wouldn’t know this, but Santi and I just spent the last hour and a half together talking while we were setting up this recording. We probably recorded a podcast before the podcast.

We talked about literally everything, from his life in Monaco to driving Ferraris to his birthplace of Mexico and how that impacted his investing. I wasn’t going to start there, but now I kind of need to ask you about it. You probably don’t know this: he doesn’t have an accent, but he was born in Mexico.

Santiago Santos

Yes, fully. Most people think I’m American. You make a conscious choice. Growing up, I was like, “Okay, how can I perfect the accent?” It’s like, how badly do you want it? For me, it was, “I just know that if I have an accent, consciously or subconsciously, someone’s going to judge you.”

One of the things my parents always made me believe growing up was that they didn’t give me much money; they provided education, and we had the fortune of traveling. They kind of instilled this idea of, “You can do anything.”

Before then, growing up, the Internet was kind of not around, so you didn’t really have as good an understanding as you have today of what’s happening in the world. Right now, it’s very anxiety-inducing because you see huge success outside your village.

But back then, my parents were like, “Look, you want to be the best? Okay, well, we can.” If you quite literally go to the investment committee and say, “I want to go and take a summer class at Harvard Summer School” in middle school, they’re like, “Okay, we can do that.” But you have to go to the investment committee for those kinds of things.

For me, it was always, “I don’t want to be the best in my school. I want to be the best in the country.” If I can be the best in the country, you just work backward from who is the best ever.

And then, for me, it was like, “Okay, if I really want to win the game, I need to remove these things that are going to inherently put me at a disadvantage.”

Jonah Van Bourg

So you actively worked on the accent?

Santiago Santos

Yes.

Jonah Van Bourg

You were sitting there practicing words, or what was the process?

Santiago Santos

You listen to yourself. You listen to how other people speak, and then you record yourself and look at yourself.

I never understood it. Anyone can perfect their accent. I hate to say it, but it’s kind of lazy if you have an accent, unless you’re conscious of it. Some people might say, “Look, I love my heritage,” but you can talk like this and there’s inherently a communication barrier.

You want to be very articulate, and if you’re sitting across from someone, you want to make sure that they understand you, because you want to remove any sort of degradation in the message. I think accent just computes into that equation, and I recognized that early on. I was like, “I definitely need to remove my accent as quickly as possible.”

Jonah Van Bourg

I think what they call that in Internet speak is “high agency.” This is something that I think is really important in the world of AI, which we’re going to get into.

But I want to start with the fact that you are known for talking about crypto, and you are known for starting a company called Inversion, which was going to invest in crypto companies. You were previously a partner at ParaFi, which is one of the best-performing hedge funds in the space.

2. Why Crypto Actually Matters Outside America

A lot of people ask: Is crypto useful for first-world countries? Is it useful? Is Bitcoin useful if you live in America? You come from Mexico. Is that one of the reasons that you got interested in crypto? Is it more useful for countries outside of America than it is for your average U.S.-born citizen?

Santiago Santos

100%. You travel, right? Anytime you travel, you understand that the financial system really breaks down. Anytime you travel, anytime you go to the airport, you try to change money.

For me, the friction pisses me off. In your day-to-day interactions, if you want to be a good investor, observe where there’s friction. Anything that’s not seamless, that doesn’t feel effortless—that’s what you should be paying attention to.

Humans, I think there’s this anxiety, this shaming in society around liking leisure, as if it’s a bad thing. I moved to Europe from the U.S., and they sort of know how to live life here. Ancient Athenians had a whole class of people who were just paid to think, and there wasn’t this shaming of grinding culture and glorifying it. What’s the point of life if you don’t have time for yourself?

I think the calculus is there: Can I have leisure? Can I have time to myself? Can I think and not feel like I’m missing out or I’m not working hard?

Jonah Van Bourg

Right. No, it was more so this: I think a lot of people talk about what good crypto is, right? What is the actual value of crypto? I think people are sort of lost on that.

One of the things that is often brought up is the case of a non-sovereign digital currency that’s useful, or remittances, or whatnot. More importantly, to take it back to the beginning and ask a more succinct question: How has growing up outside of a first-world Western country impacted your approach to investing?

Santiago Santos

Totally. There’s very little financial opportunity and inclusion. Remittances are the first or second source of income for Mexican families, and if you do the calculus, they get ripped off every time money moves from the U.S. to Mexico. It’s at least 5% or 6%. You’re like, “There ought to be a better way of doing things.”

This is my point around friction. Everything in our lives has become seamless with technology. The cost of production has gone down dramatically—Internet, mobile, all of these things have gotten better—except for certain pockets of the economy, where our day-to-day interactions still, by design, have a lot of friction.

Finance, I would argue, especially outside the U.S. and in developing countries, is very inefficient. For me, Bitcoin was an asset that presented the opportunity to move money cross-border faster, better, and cheaper. You had to hedge, but if it’s fast and instantaneous, to me that was the aha moment, and to this day it still is.

Now, through stablecoins, everything else is TBD, but that is a killer use case and will continue to be a killer use case no matter what the price of Bitcoin is. People want dollars; they’ve always wanted dollars. Give them dollars, especially in digital format.

Jonah Van Bourg

It’s kind of interesting because your path didn’t start in crypto, so you’ve actually had a couple of different careers. When I was doing some research on you, one that stood out to me was that you actually spent 3 years in biotech, and biotech is coming back in a big way.

When you look at all of the things that are happening right now, talk me through how you got into crypto. When you were first starting out, how did you get into this world? Take me through your journey.

Santiago Santos

Usually, it starts with some sort of trauma. Talk to any founder, talk to anyone—there are key inflection points in your life, and everyone has trauma.

For me, my middle sister got sick. I’m the youngest, and I’m incredibly grateful—it could have been me. I’m sitting there after investment banking, following the cookie-cutter path: 2 years of investment banking, 2 years at a growth equity fund.

Life’s sort of laid out. You could stay there and make a good living, but at some point, after making a certain amount of money, you’re like, “Okay, what else can I do with my life? Is this the most fulfilling, rewarding thing?”

You trade less money for more relevance, and that’s something we’re going to come back to in this entire podcast. You will always trade more relevance for a little less money after a certain level of fulfilling your hierarchy of needs.

To me, I don’t necessarily think that I want to be investing in growth-stage companies and technology, like the next Salesforce.

At some point, it just didn’t move the needle for me. By that time, I’d already discovered crypto, and one of the things that has always bothered me is this idea of friction. I think crypto can become a new operating system that removes friction, combined with this idea that the world is incredibly unequal. Mexico is one of the more unequal places in the world. So is Brazil.

After traveling a lot, you really appreciate the inequality, and unfortunately, technology just increases inequality. That’s the bear case of AI: if you look at inequality in a place like the U.S., since the global financial crisis, it has only gone up. I think it explains a lot of the phenomena that are happening. You have an affordability crisis, and you have the rise of social media.

All of these things—I think if you really want to understand the world, for me, it’s always been, “How do humans conduct themselves, and what’s the psychology behind that?” I think we are unfortunately in a crisis of affordability combined with extreme connectivity, so you understand what the other person has. Look at any coup d’état in the history of the world: systems fail when people understand that they are very disadvantaged, and the system is not working for them.

I keep coming back to that. Anything in my life right now is about asking, “Where can I have the most amount of impact?” I think you and I grew up and discovered crypto reasonably early on. I didn’t consciously understand it at the time, but it felt very exciting to enter into a field where there was no expert and think, “Okay, I’m going to cut my teeth here.” It’s very rewarding.

I also started noticing—I was living in San Francisco at the time—that the smartest people started to pay attention. They started to talk about obscure forums and Reddit chats. Some of the smartest cryptographers and people at Stanford were paying attention, and you were like, “Okay, there’s something real here.”

That was very much at odds with what you would hear if you went and talked to someone in a social setting. They’d be like, “Oh, wow, crypto was drug money and the Silk Road. Are you really sure you want to do that?” My mom, I think, broke down in tears when I told her that I was interested in this stuff.

Jonah Van Bourg

I had a similar story, although mine was mostly about health insurance. My mom was really freaked out that I wasn’t going to have health insurance.

Santiago Santos

Really? It’s a common theme. You have to lose all these benefits.

Jonah Van Bourg

Yeah. But you have to put yourself in the frontier. If you’re young, you have very little to lose. If you look at the asymmetry of that trade, especially when you’re young, you can really put yourself out there. There’s very little downside, with potentially infinite or unbounded upside.

Santiago Santos

That was true in crypto. I felt that in crypto, and I said, “What’s the worst that can happen?” The worst that can happen is Bitcoin kind of dies. I have this sort of deviation, this tangent in my career.

Jonah Van Bourg

How old were you at the time?

Santiago Santos

I was 24, I think. I started investing in crypto right after college, and then, yeah, I was around 24. I was like, “What’s the worst that can happen?” It obviously felt really uncomfortable. On any given day, when the market’s up or down 20% or 30%, you’re like, “Oh, okay.”

3. Marginally Delusional: How Outsiders Win

Avi Felman

Yeah, no, it’s tough. I think one of the things that drew me to crypto specifically is that it was a low-hierarchy industry. I think looking for low-hierarchy industries is very important. What do I mean by that? I specifically mean that anyone, if they’re competent, can really make an impact.

It’s very hard to make an impact, even if you’re exceptionally competent, in basically any industry. If you’re in the consulting world, it doesn’t really matter how competent you are—you’re not making an impact for a lot of years. In crypto, if you’re the best of the best, or now in AI if you’re the best of the best, you can make an impact.

I think AI is breaking down these barriers, and I want to ask you about that. The world almost seems flatter now because of AI in many ways, and you’ve been a power user. You actually wrote a great article on this, and I want to get your take on how you think AI is changing the world right now.

Santiago Santos

I think experts are overrated.

Avi Felman

Mhm.

Santiago Santos

And generalists—we can talk about what the word “generalist” means—this is the time to be marginally delusional and apply yourself. You can do anything. That’s sort of been true since the internet happened. You have the Library of Alexandria, which is called YouTube. You don’t need to go to an educational institution.

Credentialism is still a thing, but I definitely agree with you: crypto is open source, and I found people in crypto were more willing to share knowledge with you. I’ve benefited immensely from people who were earlier than I was and just taught me the ways of private-key management.

Jonah Van Bourg

How do you parse that out of people? How do you get people to share information with you?

Santiago Santos

There’s an art to asking questions, and there’s an art to being especially curious when you’re young. If you reach out to someone who understands human psychology, people love talking. If you give someone a space where you’re genuinely curious and interested in what they’ve done—“It seems like you’ve been incredibly successful. What were you doing here?”—they’re going to open up and share with you their life story and insights.

I think far too often—and I’ve been guilty of this; I don’t do enough of it—people don’t realize there’s no downside. If you see someone successful, no matter who they are, you can probably, as far as I know, send them an email or go where they are and position yourself through that. Something good comes out of it.

You go talk to someone and say, “I’m really interested in your career.” If you’re young, they’re going to take you up on that, probably more than you would think. I’ve seen this every single time. We’re a social species. If you understand human psychology, then you’ll be good at everything else.

This is why I say that if you look at the history of innovation, it’s mostly people from the outside. It’s mostly people who were delusional. Elon Musk is not a space or aerospace engineer; he just has this ability to wield power and stake a grand vision. That inspires people.

If you’re like that, it doesn’t require you to go to Harvard. What does it require? It just requires you to look at yourself in the fucking mirror and say, “I can do this.” Unfortunately, it’s your parents, your grandparents, or the school system that tells you that you can’t do it, and you just have to snap out of that. At some point, I realized my parents were not right.

Jonah Van Bourg

Yeah. You know, your mom was not right.

Santiago Santos

It’s true. I looked back, and I said, “Mom, I love you. Do you have confidence that you raised me in a good way?” She answered, “Yes.” I said, “Okay. That’s all I need to hear.”

I only need you to love me. If I have a royal fuck-up, I can come back here and still sit down for dinner, and you will show me love. I think that just inspired an immense amount of risk-taking appetite, because now that I think about being a parent, all you need to do for your kids is give them time, love, and a support system. Not money, but time, and make them feel like there’s a net that will catch them if they fall.

I had that privilege. I didn’t really realize it at the time, because I felt like my parents were just weird in the way that they raised me. But looking back, I’m incredibly grateful for it. It’s the reason why I credit all my success to that singular moment of thinking, “Okay, I genuinely think that anything is possible.”

I don’t want to go to sleep anymore, especially now. I’ve learned more in the last 6 months. You talk about AI.

Jonah Van Bourg

We’ll get into it.

Santiago Santos

It’s like a renaissance. It’s the most exciting time of my life.

Jonah Van Bourg

I think what would be fun for people to hear is: what was the first big risk that you took with your life, and how did you feel while you were taking that risk? Walk us through your calculation.

Santiago Santos

I don’t think I was that calculated back then.

Jonah Van Bourg

That’s not a bad thing, by the way. Sometimes you just need to—

Santiago Santos

I think grossly miscalculating risk is obviously a thing. Maybe I’ll go as far as saying I don’t think you really want to know the true risk, and this is the fault of experts.

Avi Felman

Mhm.

Santiago Santos

You ask experts, and they’re like, “This is not the best.” They’re paralyzed because they maybe know too much. You have to be marginally delusional and naive about the risks out there.

The biggest risk I took was probably—I don’t know, there were so many. I guess the first one was probably going to talk to a girl.

Jonah Van Bourg

Oh, yeah. We were actually talking about this prior to the podcast.

Santiago Santos

I was super shy.

Jonah Van Bourg

Santi’s dad used to make him go up and talk to girls in bars. I mean, that’s good training.

Santiago Santos

My dad looks at me and says, “Okay, you understand business.” I was a J.P. Morgan banker at the time, and he says, “Why are you so shy when it comes to social interactions?” I was like, “I don’t know.”

It sucks to be rejected, right? The fear of rejection is probably the biggest bottleneck to unlocking potential. I wasn’t very good. To this day, I’m not particularly good at being that kind of person who goes up and talks to someone.

People have a fear of public speaking. To me, it’s fear of speaking privately, because I value my space, and I never want to intrude on someone’s personal space. If they’re deep in thought or what have you, I never want to be perceived that way. But, yeah, my biggest risk was going and asking a girl to dance at a likely quinceañera or something.

Jonah Van Bourg

I mean, that’s a good place to start. A really good place.

Santiago Santos

You’re chatting: “Hi, how are you?” Cringe stuff.

Jonah Van Bourg

Yeah. No, for sure.

Santiago Santos

It has to be that. It can’t be some, “I made an investment in Bitcoin.” Definitely not. That felt like a walk in the park relative to the sweat and the anxiety of—

Jonah Van Bourg

It’s amazing how these basic things can still affect us so deeply. It’s like, yeah, bet my entire net worth on a coin that just launched yesterday in 2021. Sure, why not? Go talk to the girl on the subway who’s really pretty. Wow, that’s super difficult.

But it’s funny that you say public speaking is easier for you than speaking privately. But you worked on that.

Santiago Santos

Yes.

Jonah Van Bourg

And I think this is a common theme with you: You tend to really think deeply about things and work on them, and try to come out the other side as a better and more well-rounded person because of it.

4. "We Haven't Found A Sector": Killing His Own Thesis

This actually leads me to my next question. You started a company called Inversion, right? Or a fund. The premise of this fund was to go find companies that crypto technology was going to massively impact and change, and then potentially go buy them out, integrate crypto technology, and resell them.

Maybe it’s a tough question, but it’s been a few years, and I haven’t seen anything. I know you’re working hard. So, what’s going on there? What’s happening behind the scenes?

Santiago Santos

We’ve been incredibly busy looking at 20-plus sectors where we felt that crypto, particularly stablecoins, could meaningfully transform that business.

It’s structured as a company, like a holding company, for a very intentional reason. Having been at a fund or multiple funds, you’re just going to be more trigger-happy. You have committed capital, and the clock starts ticking. So I had an analyst, and he’s like, “Well, we need to deploy.”

It’s incredibly demoralizing—not incredibly; it is demoralizing—when you do a lot of work in a particular sector and there’s some sunk-cost fallacy where you want to do a deal. You’re trigger-happy. But my first and only order of business is protecting shareholder capital. There are just times when, if it doesn’t clear a return—meaning, if I can’t outperform the benchmark—I’m not going to make an investment.

So I sent out an investor letter yesterday to our shareholders, and I said, “Look, we haven’t found a sector.” My mistake was that filtering for crypto has led us to evaluate businesses that are more fragile than businesses that I would want to own.

I’ll give you an example of that: remittance companies, going back to this idea of why I like crypto—moving money cross-border. Remittance companies have a place in the world. It’s been a challenging business. If you look at any remittance company, either Remitly or Wise, they’re not making money. The unit economics are not great.

Even though fees have come down, the larger ones and the smaller-scale ones need to have a huge regulatory footprint, and they have no pricing power. They’re agents, and the people who break the laws of physics of making money available simultaneously in 2 parts of the world are agents and fulfillment partners. The intermediary there is the remitter.

What we’ve observed is that a public, larger remittance company says stablecoins are going to transform its business and release all this working capital. So, message received. I then go talk to a representative sample set of similar remittance companies and bring in founders of companies within the crypto universe that are trying to build this network of moving money across borders. At the end of that, we can’t make this business more efficient.

I don’t think there’s a group of people in crypto or elsewhere that have gone as far as we have to really try to understand where crypto is going to fit in, especially for businesses. That’s not to say that the technology isn’t real. That’s not to say that there can’t be good, profitable businesses. I’m talking about businesses that are not crypto-native.

Certainly, you could look at Binance, Tether, the exchanges, and likely Hyperliquid of the world. They are the new entrants, and there’s no question that those are phenomenal businesses. But when it comes to traditional businesses—FX, credit, tokenizing part of their book—I think a lot of times—well, not a lot; in every instance—we weren’t convinced that the impact of the transformation was sufficient and commensurate with the risk that we would be taking.

When you’re doing turnaround stories and trying to fix businesses that are inherently challenged, the bar is much higher, right? You’re probably going to underwrite a base case that’s still overly optimistic. So we need to see—or I need to see—a very healthy margin of safety to make that investment, and we haven’t done that.

So I went out to my investors yesterday and said, “Listen, guys, this is what we’ve learned in this entire journey.” And, by the way, I end by saying, “If you have evidence to the contrary, of crypto really fitting in, I would like to know now.”

Jonah Van Bourg

Mhm.

Santiago Santos

Because I’d rather be proven wrong now. If not, I definitely think there’s a huge opportunity in just buying good businesses.

5. Buy Boring: Why Technology Is Orthogonal

I think Warren and Charlie were smart because they just found really good operators, gave them money, and just compounded. So that was my mistake. I think Inversion—I’m still going to keep going, by the way. Inversion, to me—

Jonah Van Bourg

How do you keep going?

Santiago Santos

You keep going by buying good businesses.

Jonah Van Bourg

So forget crypto. You’re now a PE firm.

Santiago Santos

Technology is orthogonal. If you buy a good business that has moats and pricing power, and you just implement technology, that’s a better business.

What I found is you definitely want to start by first looking at businesses that have produced meaningful cash flow through any market environment. That’s a good business. Is there disruption risk from technology or elsewhere? That’s just it. You don’t want to buy anything else, and if you can’t find it, don’t invest. Buy the benchmark.

There are a couple of things that are always going to be true. There are a bunch of businesses that have no succession plan, right? People are retiring. There’s a huge opportunity in Germany, Japan, and the U.S., but we mostly focus in the U.S. just because of rule of law and what have you.

We want to buy smaller businesses that have proprietary data sets. For instance, I’ll give an example: critical power.

Jonah Van Bourg

Okay.

Santiago Santos

Every hospital, school, and hyperscaler needs to have critical power, like a generator, in case power goes down. The grid’s not getting any better. Jonah right here can tell you that.

They need it. It’s federally mandated that you need to have critical power and these generators, and there are people who go and service them on a regular basis. A big part of the revenue is contracted. It’s not going to go away no matter what happens. No matter what latest model comes out, that generator needs to be constantly serviced and inspected. If not, you go to jail.

Jonah Van Bourg

That seems extremely high-stress. So if you don’t maintain it properly, you go to jail?

Santiago Santos

The people in charge of the hospital are in breach of their fiduciary responsibility. By law, you need to have these critical power units, and you need to have—

Jonah Van Bourg

Okay. So there’s an industry out there that is mission-critical because if you don’t get it right, as a hospital administrator, you can go to jail. I’m repeating that because we’re going to clip that.

Santiago Santos

Yeah. Incredibly fragmented, with geographic constraints, right? You have to service these markets. It’s in high demand, and there are labor shortages.

Jonah Van Bourg

Okay.

Santiago Santos

And so that’s an example of a business that is like software but better, right? It has contracted recurring revenue, all-weather. And, by the way, there’s a lot there that could be optimized with AI.

Jonah Van Bourg

Right.

Santiago Santos

Since they have routing and scheduling, and just a whole—like, the way they even produce the reports to their clients—all of that, on the margin, is very key to having a margin uplift in that business and having the capacity to take on more clients.

Most of the businesses we’ve talked to—we started this a couple of weeks ago—they all say the same thing: “We don’t have enough people on staff, and we find that there’s a delay in the time that we can dispatch and service.” A big part of our revenue is that we can bill 3 or 4 times the rate for emergencies, so it’s a scheduling issue.

Oh, well, I think there’s a solution: You buy that type of business, implement good practices and better scheduling, and they don’t get paid in time, so there’s factoring there.

So what I'm trying to say is I feel incredibly comfortable going after this type of thesis. There's always going to be an opportunity to acquire a business, implement best practices, and utilize technology that benefits the business. But, just to crystallize the one-liner, the mistake that I made was thinking that technology is at the center of why you want to buy a business. It's orthogonal, meaning it enhances, but you still have to buy a good business. I don't want to buy it. It's as simple as that, right?

6. The Only Fund Manager Who Wouldn't Deploy

Jonah Van Bourg

I mean, when you say it like that, it's extremely simple. But I think people can often muddy what makes a good business a good business or what makes a good investment a good investment. When I was working at all the previous hedge funds I was at, I always used to say, “You need to be able to summarize your pitch in a paragraph. If you can't do it, then it's probably not a good investment.”

People can overcomplicate it, but there's so much in what you said that I think our viewers are going to want to dive into. Number 1 being: you were a fund manager, and every fund manager wants to deploy capital because that's how they get paid, and you didn't. You're probably the only fund manager that I've ever—I've talked to a lot of fund managers, Santi. There are a lot of people who, behind closed doors, are going to say, “Yeah, well, I don't really believe in the thesis anymore, but I've got $100 million to deploy. I've got to deploy it.”

Santiago Santos

Well, they're charging 2%.

Jonah Van Bourg

Right. Exactly. Was it hard for you?

Santiago Santos

Well, I'm not charging 2%.

Jonah Van Bourg

Okay. Do you think it would have been different if you were?

Santiago Santos

Of course. No matter how you look at yourself, you can't look at yourself in the mirror and say your incentives are not going to change. You're deluding yourself, right?

Jonah Van Bourg

That's very refreshing, honestly. And I think it's true. Again, if you understand your psychology, I just knew that if I start a fund and go from a $20 million fund to $2 billion, you bet your last dollar that my psychology will change. The way I think about investing will change. So you become less of an investor and you become an asset manager.

You go look at the larger private equity funds and larger investment firms. They've done that. Benchmark and others have held the line on saying, “We actually think this is a sensible right size for the opportunity we're attacking.” I appreciate that Benchmark has now raised a larger fund, but for a long time they kept their fund at around $300 million or $400 million.

In crypto, I think we should talk about generalists and experts, because crypto, for instance, is that type of industry that will constantly tempt you to take a shortcut that is somehow going to contradict your core values and principles. There's always that—

Santiago Santos

That's, I think, been a big topic of discussion around tokens and equity, and we need to hold the line.

Jonah Van Bourg

Yeah. So maybe dive into that. Why were the incentives in crypto wrong? Did crypto fail because these incentives were incorrect, or was it always going to run into these issues?

Santiago Santos

Well, crypto doesn't fail. I want to make clear that I can simultaneously love the technology and be incredibly bearish about valuations and other stuff happening, which is not inherent to crypto. There's fraud everywhere. There are scams everywhere. There's an incentive problem in every industry, especially in finance, in healthcare—everywhere.

Jonah Van Bourg

Is the incentive problem worse in crypto, though?

Santiago Santos

I would say no. It just hurts more because it's an industry that has very high-principled values and stakes them. But the manifestation of that is just not there. And maybe it's naive, right? It's like governance. Well, you look at every single democracy, and turnout rates in elections are very low.

People just want to make things easy for people to go back to enjoying their day. That's why AI is so great, because I think we might just go into a world where there's more leisure time and you own back your time. That is the ultimate goal in life, I think: can you have time and freedom, and nothing else?

Jonah Van Bourg

Mhm.

Santiago Santos

Yeah. But my biggest fear is, are you going to slow down? And I think, no, on the contrary.

Jonah Van Bourg

We can get to that. But back to crypto, I think there's this double standard. The implementation of it gets distorted, and that is painful for sure. You look at people talking publicly: “Oh, real-world assets are all the rage. We want to do transformative finance,” and then they prioritize meme coins.

I don't have anything against memecoins. I think, again, in an affordability crisis, people buy more lottery tickets. In a bear market, in recessions, people want to get out of there. It's a very primitive thing to want. Memecoins are just a manifestation of it. Crypto is empowering it because crypto sort of opened the floodgates to people who otherwise wouldn't have access to investment products and don't have them in their local economies and markets. Crypto is just that way to express that. It's sort of like open markets—laissez-faire.

Santiago Santos

I'm pretty laissez-faire. Just let markets kind of run amok, right? But I think, as an industry, we can definitely do better. We can self-regulate. We can self-police. The Token Transparency Act is a good example of that, right?

We don't need—for so long, we blamed a regulator for the fact that crypto is not taking off. Now that excuse has kind of gone away, and it's like, well, we can definitely, as an industry, look at ourselves in the mirror and say there are best practices that we can implement that I think will push us higher and instill more confidence and trust. It's not surprising that we're not taken as seriously by other people who are skeptical when there's just a normal way to conduct yourself, right?

Jonah Van Bourg

Like, for instance, I don't want to give specific examples, but—no, let's—we can get into it. You know what's funny, though? Whenever I talk to people like you, you're moving from crypto to a much broader set of the investable universe with what you're doing right now. Whenever we have these conversations, it's like we're talking about an ex-girlfriend that we loved so much, and now she kind of just—you know, she has BPD and she fell off the rails.

Santiago Santos

But, you know, we still have so much love and respect for her. [Laughter.] I want to go back to something you said about going to investment committee with a very clear mind, right? I think the biggest mistakes I've made in investing are trying to be clever in how I make money.

Jonah Van Bourg

Mhm.

Santiago Santos

You want to feel smart. You want to feel validated, right? Investing is, for me, the best sport in the world because it forces you to—if you want to be good at it—you're constantly learning.

And if you're managing capital, you have capital. Think about how wonderful this is: there are people who have dedicated their entire lives to solving problems, who are incredibly passionate, who don't have capital and need it, and are going to look to you for it. They're willing to dedicate 30 minutes or an hour or many weeks of their time because markets are inefficient and money should move like water, but it doesn't. Somehow, you find talent that is undiscovered and needs it, and they're willing to basically brain-dump their entire knowledge and insight onto you. That's a wonderful thing.

Unfortunately, people aren't comfortable making money without necessarily having to feel clever in doing so. For instance, you could have sat in 2021, when you and I both kind of branched off on our own, and you could have heard someone like (likely Stan Druckenmiller), who, by all intents and purposes, is someone I look up to. I think he's just one of those guys you need to pay attention to when he talks. He was at his own conference and said—I think it was the Collison brothers or whatever—he said, “Go long Nvidia.” And they're like, “Really? That's the best you got?”

Jonah Van Bourg

It's pretty good.

Santiago Santos

And right now, that's pretty solid. That's a guy who—I don't know him personally, but I feel like he's incredibly at peace with (a) changing his mind and (b) not holding himself to an identity. He doesn't have an identity crisis of, “I'm a crypto investor.” No, no, no. You're an investor, right? You just so happen to invest in crypto.

By the way, I think crypto, if you've been in the industry long enough, you have had to simultaneously be a high-frequency trader and a venture capitalist and understand risk, sprinting, and running a marathon. That's a great education to investing, full stop. If you don't think that you can branch out of that, you just need to look at yourself in the mirror and go to therapy and say, “It's an identity.” I've had it. I had it. I was like, “Oh, I'm an investment banker, and then I'm a private equity guy, and then I'm a venture capitalist, and then I'm now a crypto...” No. I'm like, “I love investing.”

I know I'm not good at other things. I think the faster you remove that identity, disassociate work from your core identity, and get comfortable with—not trying to be clever. I'm speaking from experience; this is not advice. Get comfortable with simply trying to uncover the truth.

Jonah Van Bourg

Just simply trying to uncover the truth.

Santiago Santos

Yep. I think they're 2 different things, right?

Jonah Van Bourg

What do you mean by that? Why is discovering the truth different from being clever? Clever people might discover the truth.

7. Make Money Or Be Right?

Santiago Santos

Clever people are likely going to try to manually distort the worldview to conform with their thought process. They're going to see new information, and they're likely going to pick apart things that confirm their bias. If you're trying to be clever—if you're in a debate, you're trying to sound clever to win the debate. In investing, it's like: Do you want to make money, or do you want to be right? You want to make money.

Jonah Van Bourg

Making money is uncovering the truth before it becomes consensus.

Santiago Santos

Sometimes, again, going back to this idea of inversion, I'm just incredibly comfortable uncovering the truth. I started Inversion because I was like, this is a hypothesis: I want to know before anyone else how big this market is. There are narratives and hallucinations about how big crypto can be. Everyone's talking about the same things. I just got tired of it. I actually want to know how big this opportunity is. Is it going to be a $1 trillion market, $10 trillion, $100 trillion, or a couple hundred million dollars?

I was sitting with, I think, one of your former bosses, and he was like, “Why are you starting Inversion?” I want to start Inversion because I want to know before you how big this market is, right, and then make that trade. And he's like, “[__].”

Jonah Van Bourg

No, that's Mike for sure.

Santiago Santos

I'm not saying who it was, but that's a hypothesis. Everything for me is a hypothesis, and my role—and it's fun—is a truth-seeking business. I think the process should be that we're uncovering the truth, not trying to be clever in how we pitch it to LPs, right?

Jonah Van Bourg

I think that's fair. By the way, that can be difficult because I think some of the best fundraisers are clever, extremely clever. And you have to, as an LP—this is something maybe we can talk about—

Santiago Santos

Well, you can play the game.

Jonah Van Bourg

Well, you have to watch out for that, though. You have to watch out for the people that sound incredible but actually can't invest. Everyone should go read the “forgotten billionaires” book, because it's a book about one of the guys who was running Long-Term Capital Management, this spectacular fund of Nobel laureates that blew up because they miscalculated risk. They didn't think the Russians were going to default on the bonds, and they did.

He says, “Look, if you look at a snapshot of all the billionaires in the 1980s, very few remain today.” Why is that? There's lifestyle creep, but a lot of it is first-, second-, and third-generation people inheriting a bunch of money. You see this a lot in Europe, and they feel some sort of guilt. That explains a lot of wokeism, I think, and grievances: “I didn't make this. I need to protect it,” which is fine. But then there's an element of, “My grandfather was an industrialist and he created this.” You're in this shadow, so you want to feel clever.

Santiago Santos

Right. There's that insecurity, and people exploit that.

Jonah Van Bourg

You see this a lot, actually, in New York, especially with a lot of these trust-fund kids. They want to feel clever, so they want to do the SPV that Goldman pitches to them, right? They have the money, and so they disrespect Goldman. But it's one of those things—I think you see it a lot with people that come from money. They try to be in the new hot sector because they think it'll differentiate them and make them clever.

One thing that I want to ask you specifically, because I think you have a good read here, is that you wrote once about spiky people.

Santiago Santos

Yes.

Jonah Van Bourg

It was in your essay. For those of you that don't know, this is a heuristic for figuring out who to invest in. How do you think about investing in people? As an investor, you're not just dealing with companies; you're dealing with people, and you're dealing with their drive.

Santiago Santos

This is, again, growing up. This is an issue I have with my parents, with my mom, and I love her, but she was like, “You need to be more well-rounded.” I'm like, “That's the biggest load of [__] I've ever heard in my life. I don't want to be well-rounded. That's mediocre. That's literally a bell curve. I don't want to be rounded. I want to be incredible.”

I very quickly understood and came to terms with the fact that I was just not well-rounded. I was like, “Don't tell me that. Don't ever tell me to be well-rounded. What does it even mean?” I think this is what's wrong with education. It's a problem with how we raise kids. It's a problem with society. Yes, you need a balance of EQ and IQ, but sometimes, if you're good at something, accelerate and differentiate, right?

I think hiring and investing in people—you want to just—I just love being around spiky people that don't agree with you. They don't care what other people think. They're so driven by one particular thing. By the way, there are well-rounded people that are great, and that's not a dig on them. I just felt comfortable not being well-rounded. And it comes with trade-offs, right?

8. What A 22-Year-Old Should Go Deep On In The AI Era

Jonah Van Bourg

In today's world, it's kind of tough to figure out what to go deep on, right? When you have AI out there that can accomplish a lot of different tasks for you, it's kind of reshaping the world. What do you think is worthwhile going deep on? If you're talking to a 22-year-old today and they're asking you, “Santi, what do I spend my time on?” what are you telling them?

Santiago Santos

Young people have this, again, sort of delusion and are generally very curious. You go talk to a baby, and it will force you to really understand how very little you know about the world: Why is the sky blue? Very basic questions. At some point, the education system sands you down.

You are playing the game to get the score, and you can game these systems in the way that they've been constructed: Industrial Revolution concepts of 9-to-5 and memorization. If you apply yourself, you can get a really high score on the SAT. That doesn't make you smart. That doesn't make you a first-principles thinker. It doesn't give you agency.

Jonah Van Bourg

I've been riding on my score for a long time. Fine.

Santiago Santos

I was an SAT tutor. I scored—I gamed it. I knew how to game it. But I think the education system and society at large, for better or for worse, just sand even the spikiest people down. They stop asking questions and conform to what a system is. I just didn't have that growing up. You would talk to my teachers, and it's like: You want to be irreverent. You want to question things. I think it starts with parents, with how they raised you.

In today's world, yeah, there's probably a trade-off. I don't know what the perfect answer to that is, because I definitely experience the same as other people, which is: Am I just an inch deep? Am I a mile wide and very shallow, and not really going deep? But I think I allow myself to just get on the river and allow myself to discover stuff. Somewhere along the way, just detour, make a pause, and I think spontaneity and creativity just don't come in expected places.

I've now gotten more into the habit of, if I get invited to an event, I just say no. And I'm like, “No, I'm going to go,” because I started to realize: Just put yourself in somewhat of an uncomfortable position, and something good comes out of that. I've definitely prioritized more in-person stuff, because there's something very human in that, and behind the camera, behind the screen, it just doesn't come through.

Especially in a world with AI, I told my team at Inversion, for instance, we're a really small team. We will automate everything except judgment, and something that—

Jonah Van Bourg

How many people?

Santiago Santos

We're 3 people.

Jonah Van Bourg

And how much money are you able to disclose?

Santiago Santos

We raised $26.5 million. We spent very little of that.

Jonah Van Bourg

Constellation Software started with $25 million, right?

Santiago Santos

Berkshire started with small sums. And this is something that people want to get to the end state: “I want to be like Constellation—a trillion-dollar business, a trillion.” I'm like, “Yeah, but there's a process.”

I think the patience of just applying yourself with AI—if you're—I wake up every day, I'm like, “Okay, I want to prompt new stuff.” There's a whole cabinet.

I don’t want to go to bed. It’s like being a kid—you don’t want to go to sleep because you’re so excited about the next day. I’m feeling that.

The point that I’m trying to make is, you can, by the way, reinvent yourself. If you feel like you’ve been a generalist, it’s okay, as long as you have curiosity and remove any sort of message that you’ve received from the world, your parents, or your teachers that you can’t reinvent yourself. I love this quote: “You’re under no obligation to be the person you were two minutes ago.”

It starts with understanding who you are. This identity—this work—is not your identity; it is part of your identity. My bet is that if you’re curious and you allow yourself to just apply yourself creatively, I’m very long creativity with AI.

You have this guy in Australia who had a sick dog with a tumor. He just kind of iterated on it. He had some knowledge of biology and then built an mRNA vaccine. The government didn’t want to let him do it because he’s not an expert and it’s not regulated. It’s all this load of crap.

Then he finally convinced the lab to manufacture this vaccine, administered it to the dog, and the dog is cancer-free. That guy’s going to build a billion-dollar pharmaceutical company based on his maniacal endeavor to save his dog. Holy shit, if you’re not looking at that and feeling inspired, I’m sorry.

That’s why I feel like the narrative on AI is so bearish. It’s like, we’re going to lose all these jobs, we’re going to be automated, and then what’s the point of life? Society’s going to become more unequal. I’m like, no, no, no, no, no.

I probably delayed starting a company many, many years because I still have sort of an imposter syndrome, which is an insecurity that I’m not technical. Before, it was like, if you don’t know how to code, just find a co-founder.

Avi Felman

Yeah, you don’t need that.

Santiago Santos

There’s always a degradation in the process of building. You have to have a team, an engineer, or find someone outsourced, and then you have to explain to them what you want that’s in your brain. There’s degradation in that assembly line.

Now you’ve basically collapsed that with likely Claude Code. Sure, there are going to be a lot of failed experiments and shit, archived things, but Pandora’s box is open. Creativity is just going to explode, and I think that’s remarkable.

Avi Felman

In the same way that you spent years figuring out what industries crypto is going to disrupt, you’re now spending time figuring out what AI is going to disrupt. I assume AI-resistant sectors are on your mind. What are your conclusions—or maybe not conclusions, but initial first impressions—of how things are going to change, what’s resistant, and what’s going to be disrupted?

Santiago Santos

I’ll tell you what smart guys are talking about. The software investors are telling you, “Software is obsolete. It’s a commodity. Services are important.” Good luck to all the software companies that just try not to have any professional services attached to them because it’s lower margin.

Avi Felman

So services, okay?

Santiago Santos

People in other tech industries tell you that hardware is back. I look at that and say, okay, all that is very human.

My point is, in a world where you can automate most processes, you want to be investing in the extremes. Definitely AI is at the forefront of that, but also what makes us very human, and that is the human experience.

You look at the tickets to the World Cup and Wimbledon—crazy, like 15,000. People are craving the offline. People are craving those interactions, so I think those types of interactions are only going to be way more valuable.

Vintage—we’re talking about cars. You don’t want the hypercar that looks like a futuristic version. No, you want the vintage one, the nostalgia factor. That, I think, is going to be even more valuable.

Avi Felman

People are sort of pining for a world that doesn’t exist, in that sense, with the cars. I mean, we were talking about the Ferraris before and how the new Ferrari—

Santiago Santos

By the way, a lot of the reasons why they’re manufacturing these cars—and I had, I think, some sort of conversation with Jonah about the Porsche and stuff—is regulation, right? This sort of woke idea is forcing especially European car manufacturers to build hybrids.

It’s like, no, no, your Porsche enthusiast wants the feel of the naturally aspirated engine. But regulations bind and force you to go down a path that is obviously wrong.

AI-resistant sectors are top of mind. No matter what happens in the world of AI, you still need to have compute. You still need to have regulations behind that, and energy, and all of that is something that just does not go away.

Healthcare is obviously, I think, going to be big. I’ve always wanted to invest in healthcare, but again, I’m not a biotech engineer, so I know my limitations, right?

Avi Felman

But I’d actually be very long pharma companies that have a lot of data. If you have a proprietary data set that you can then run the model against, those guys are going to discover things, because I heard it from someone like you: for the first time ever, you’ve had someone who can make relationships across data sets and has deep domain expertise in neuroscience, the microbiome, sleep, and cognition.

You’ve never had a single scientist with that amount of cross-domain expertise as you have with “Fable 5.”

Santiago Santos

One hundred percent.

When I was at a company likely called Elysium, we had 12 “Noble” laureates.

Avi Felman

You were collecting them like Pokémon. How did you get 12?

Santiago Santos

Crazy. Eric Marcotulli just kind of went after us, and journalists came after us, like, “Oh, this is…” Anyway.

Talking about incentive problems, the world of academia has many of them. If you talk to a scientist who’s dedicated his entire career to a specific theory of aging, and then a new body of research or a new paper comes out that disproves it—telomere length or mitochondrial health or some other theory of aging—they will be very, very defensive.

The mafia of academia is worse than any other mafia because it discredits you.

Avi Felman

Because it discredits you.

Santiago Santos

I think now the beauty of AI is it doesn’t care, and it breaks through that. For better or for worse, I think that’s handicapped our ability to do drug discovery.

Again, in investing, are you willing to put aside your ego, your credentials, and feeling accomplished and relevant to uncover the truth? It’s very uncomfortable because it sort of forces you to reinvent yourself.

If you’re 60 years old and your entire theory of what causes a particular pathology is X, and someone comes along and disproves that, I haven’t met someone who has been like, “Yeah, I was wrong.”

Avi Felman

Yeah.

Santiago Santos

But in investing, if you’re going to be as stubborn as that, you’re going to lose all your money.

I think that’s why, in every discipline, the faster you just get into the mode of truth-seeking, the better you will be and the happier you will be. It is sometimes uncomfortable, but I think spiky people just become spiky. You’re not born with spikiness.

Avi Felman

In the same way that you perfect an accent, you just—I think you just apply yourself by saying, “I want to uncover the truth.” What makes someone great? Well, observe, right?

Santiago Santos

X-ray, diagnose—not necessarily copy, but adopt elements. I think it always boils down to whether you’re willing to be truth-seeking.

The great thing about AI is—and there’s so much to talk about. I know we’ve got to wrap.

The hallucination risk is real with AI, and you have companies that are very specifically talking about model weights and information that is being served. I think that’s something to pay attention to.

For your partners in journalism, the danger—and I’m very optimistic; I don’t want to end on a negative note—is that we feel like, as we become hyperconnected, we simultaneously think that we’re informed. That’s very far from the truth, because the algorithm serves you something that is self-serving.

We are deluding ourselves into thinking that we’re informed, which means markets are more inefficient. Even experts just socialize with the same experts at the same conferences. There needs to be someone like Elon who says, “I’m going to break from all of that and just think from first principles.”

Avi Felman

And that’s the beauty. This is why this is the best moment in time to be a generalist, because if you just wake up and prompt and say, “I want to understand this—”

Santiago Santos

Genuinely. Then you look at the history of innovation. All the major discoveries either happened by accident or were made by people who were not in the same field: penicillin, stem cells.

Avi Felman

Because it gives you a new way of looking at things.

Santiago Santos

AI just accelerates that, so—

Avi Felman

It is—

Santiago Santos

AI is the new way of looking at things, I think. That’s—

Avi Felman

That’s how I would synthesize that, and that’s why I’m so excited. Santi, thank you for coming on the pod and being truth-seeking. This was really fun. That was a serious conversation; most of our conversations have a lot more smiles. But seriously, thank you for coming out and talking to me.

Jonah Van Bourg

This was an awesome conversation. I'm super excited for all you guys out there to hear it.

Santiago Santos

Thank you. We should do this more often.

Jonah Van Bourg

Absolutely.

心理、价值与数据:Santiago Santos 如何穿越市场 — 文字稿与摘要 | BidClub