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All-In

Industry veterans Chamath Palihapitiya, Jason Calacanis, David Sacks, and David Friedberg cover economics, technology, politics, society, and poker.

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59 episodes2 active
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All-InEN · 51 min

Daniel Ek: Life After Spotify, Broken Healthcare Incentives, Catching Disease Early & AI's Potential

Daniel Ek

Spotify passed 700 million active users and 300 million premium subscribers; Daniel Ek became executive chairman January 1 and returned to building.Neko's $499 unit-economic-positive visit combines 53 blood markers, 6,000 images and clinician review in roughly an hour.Over 100,000 scans found serious, previously undiagnosed conditions in roughly 1% of members; population outcomes and budget effects remain unresolved.

All-InEN · 37 min

Satya Nadella on the AI Doomer Slowdown, Microsoft’s Master Plan & Who Wins AI

Satya Nadella

Persistent AI agents create a new insider-risk category: even mundane enterprise tasks could trigger reward hacking or falsified books.Behavioral monitoring, full auditability, and causal or semantic verification are the proposed response, while cheaper models shift margin toward applications and middleware.Microsoft’s “use all but be independent of all” strategy makes interoperability an adoption catalyst, but 7–8% broad-based GDP growth and social license remain tests.

All-InEN · 64 min

Elon Musk & Gwynne Shotwell on AI Risks and Peer Review, Starship, Terafab, SpaceX/Tesla Merger

Chamath PalihapitiyaJason CalacanisDavid SacksDavid FriedbergGwynne ShotwellElon Musk

Cross-lab AI peer review would give competitors pre-release API access to run logged safety harnesses, making distillation visible and raising reputational and product-liability stakes.Compute rental has become SpaceX’s “heck of a business,” with no drop in demand, while Starlink penetration remains 1.5–2%.Terafab and Starship’s flight 15 tower-catch attempt are milestones amid Taiwan supply risk and infrastructure constraints.

All-InEN · 47 min

Jensen Huang: The Doomer Hoax, Superintelligence is Here, and The Future of AI (ft. President Trump)

Jensen HuangPresident Trump

Jensen Huang cites failed forecasts on radiology, AI-generated code and entry-level jobs to challenge doomsday narratives, while arguing that AI incidents so far call for root-cause engineering and independent evaluation rather than sweeping regulation.With 80% of AI-native companies receiving $400 billion in recent venture funding using open models, NVIDIA is building infrastructure bottlenecks as Jensen predicts China will reach advanced lithography by 2030, leaving commercialization, lab controls and data-center execution to monitor.

All-InEN · 96 min

AI Kills Everybody or Doomer Psyop? OpenAI’s Math Breakthrough, Nike’s $200B Collapse

Chamath PalihapitiyaJason CalacanisDavid SacksDavid Friedberg

Anthropic’s IPO faces a disclosure test after Evan Hubinger endorsed a greater-than-10% extinction probability, despite Polymarket’s 88% odds.Sacks argues rapid amplification may reflect a coordinated campaign targeting open-source weights, though that remains his interpretation.OpenAI’s Navier–Stokes result shows brute-force leverage, while data-leakage risks favor sovereign deployment and Nike’s 80% decline underscores a product, channel, and brand reset.

All-InEN · 92 min

GPT-6 Hits AGI? Tech Euphoria 2.0, SF Mansion Shortage, NYC Bans AI in Schools & Venezuela Oil Deal

ChatGPT-6 (“Astra ASI”) is rolling out to limited organizations as the panel treats AGI as present, with rivals potentially catching up within “the next 3 or 4 months.”Falling intelligence costs may make non-frontier models commodities, while real revenue fuels 1998-style euphoria; Nvidia’s prospective Hugging Face transaction could bolster open competition through cheaper sovereign compute, with regulation a key risk.

All-InEN · 69 min

The Robot Episode: Four Leaders on What's Coming

Péter FankhauserBernt BørnichAmanda McMasterJonathan Hurst

Industrial robotics’ first validated wedge is data, not labor replacement: ANYmal and Spot can support roughly $100,000-$300,000 prices when avoided downtime or leaks protect losses measured in hundreds of thousands per hour.The $1-an-hour worker remains a scale end-state requiring $20,000-$40,000 hardware and 40,000 hours, while 1X’s handful of $500-per-month NEOs in 2026 will test autonomy, safety, and trust against Chinese hardware.

All-InEN · 94 min

The Fight Over Open Source AI, Anthropic's $1.5B Payout, NYC Socialists: Evictions = Violence?

Chamath PalihapitiyaJason CalacanisDavid SacksDavid Friedberg

A US ban on Chinese open-source models could impose a 50-100x AI input cost premium on domestic developers while failing to stop distillation, creating a policy-driven “token tax.”With models reportedly matching published performance within weeks, 95% of real work may be served by many models, shifting durable value toward applications, clouds, and chips while Anthropic’s $1.5 billion settlement leaves training legality unresolved.

All-InEN · 42 min

Mark Cuban on the AI Bubble: Who Actually Gets Wiped Out?

Mark CubanChamath PalihapitiyaJason CalacanisDavid SacksDavid Friedberg

The AI bubble’s likely casualties are VCs, funds, and PE firms concentrated in peak-priced private rounds, while infrastructure spending depends on whether token economics and video demand justify today’s buildout.Enterprise implementation remains the bottleneck as agents drift and require forward-deployed talent, but falling build costs are opening bespoke software and IPO-funded acquisition strategies for smaller AI companies.

All-InEN · 50 min

Former Intel CEO on What Went Wrong, What's Next + Lovable CEO on the Real Promise of Vibe Coding

Jason CalacanisPat GelsingerAnton Osika

Pat Gelsinger attributes Intel’s decline to replacing technical leadership with spreadsheet-driven capital allocation, while Apple, Nvidia and TSMC compounded patient capability-building into durable platforms.The semiconductor recovery remains exposed to Taiwan’s energy dependence, even as AI’s long runway is constrained by electricity; Lovable meanwhile reports production-scale adoption, with defensibility shifting toward orchestration, security, operational data and user feedback.