All-In

Chamath Palihapitiya × Aaron Cowen × Dan Dreyfus × Oleg Nodelman × Kyle Samani × Jason Calacanis × David Sacks × David Friedberg

MGM’s $48 bid offers a near-term floor while Osaka and possible Dubai legalization create asymmetric upside, whereas Talen monetizes a 2 GW nuclear and 6 GW gas portfolio amid a projected PJM power shortage.Aktis remains a binary 2027 clinical platform wager, and GEODNET links revenue to token purchases; portfolio sizing ultimately turns on liquidity, downside, regulatory intervention, and whether satellites displace terrestrial RTK.

Dan Dreyfus

AI, reshoring, defense, and electrification are colliding with decades of infrastructure underinvestment, turning critical minerals into a supply shock against surging demand.China’s export restrictions exposed near-term shutdown risk, while Washington’s equity, permitting, and floor-price offtake package could finance new mines; copper supply may still lag enough for prices to double.

David Friedberg

OpenAI missed its 1 billion weekly-active-user and 2025 ChatGPT revenue targets, but ChatGPT 5.5 and Codex are gaining developer momentum as Opus 4.7 struggles.Power—not demand—is the AI choke point as four hyperscalers guide $725B of 2026 CapEx, shifting leverage toward capacity suppliers while pressuring free cash flow.

Chamath Palihapitiya × Jason Calacanis × David Sacks × David Friedberg

SpaceX’s proposed IPO would raise $75 billion at a $1.75 trillion valuation, potentially creating the external mark Chamath sees as necessary before a “99.999%” likely Tesla combination.That merger would unify xAI, robotics, chips, factories, launch, and satellite communications, while SpaceX infrastructure could support orbital logistics, stations, mining, power generation, and communications.The IPO window may narrow as SpaceX, OpenAI, and Anthropic absorb finite capital, while Friedberg estimates Bitcoin has five to seven years to complete quantum-resistance migration.

Chamath Palihapitiya × Jason Calacanis × David Sacks × David Friedberg × Brad Gerstner

Brent’s swing from $84 to $119 and back toward $100 pushed Goldman Sachs’ PCE forecast from 2.1% to 2.9% and GDP growth down 30 basis points, while oil’s fall to $90 suggested a short disruption.AI revenue is accelerating as Opus 4.6 and ChatGPT 5.4 shift spending into labor budgets, but durable demand remains disputed amid canceled data centers and backlash.

Chamath Palihapitiya × Jason Calacanis × David Sacks × David Friedberg

The panel’s most aggressive macro signal is 5%-6% U.S.GDP growth in 2026, supported by AI productivity, tax refunds, capital investment, and possible rate cuts, while California’s proposed 5% wealth tax creates a migration and asset-pricing risk.Copper, Polymarket, Huawei, and Amazon supply the clearest upside calls, but software maintenance, entry-level white-collar work, oil, the dollar, and California luxury property remain key disruption or downside themes.

Gavin Baker × Ben Shapiro × Phil Deutch

GPT-5 was OpenAI’s first launch that failed to decisively beat rivals, with Grok 4 ahead on key benchmarks, though its router may simplify mainstream AI use.Hyperscaler returns and fully utilized GPUs support continued capex, but power, China’s manufacturing coordination, tariff uncertainty, housing costs, and Apple’s $700 billion buybacks remain critical allocation signals.

Chamath Palihapitiya × Jason Calacanis × David Sacks × David Friedberg

Trump’s targeted strikes and ceasefire reduced the feared forever-war risk, while oil rising only from roughly $60 to $74 suggested markets priced a less chaotic Middle East.Mamdani’s New York upset exposed an indebted, “negative capital” generation, and the panel linked his urban-socialist platform to student debt growing from $500 billion to $2 trillion.Stocks reached all-time highs amid a split between weakening breadth and possible liquidity-driven upside, while early FOXO3 cell-therapy results and AI copyright rulings leave major scientific and legal risks unresolved.

Chamath Palihapitiya × Jason Calacanis × David Friedberg × David Sacks × Thomas Laffont

Trump’s opening week reset national strategy around energy, technology and private capital, with DOGE confronting agencies’ spending incentives and Stargate proposing $500 billion for AI infrastructure.The decisive tests are whether compute earns an adequate return, whether electricity and nuclear deployment can scale, and whether TikTok’s proposed ownership structure avoids government picking winners.