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PERSON DIRECTORY

Jim Collins

Jim Collins appears in 1 indexed conversation across The Cognitive Revolution. This directory brings every appearance, source, TL;DR, digest, and transcript into one searchable feed.

1 EPISODE1 SHOW
1 episode
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The Cognitive RevolutionEN · 85 min

AI Discovered Antibiotics: How Small Data & Small GNNs Led to Big Results, w/ MIT Prof. Jim Collins

Erik TorenbergNathan LabenzJim Collins

A 2,500-compound dataset and graph neural network raised antibiotic-screening hit rates from below 1% to 51%-52%, producing halicin after screening 6,100 additional molecules for efficacy, safety, and novelty.AI can search chemical spaces no laboratory could physically cover, but clinical trials remain the dominant cost and models still struggle with solubility, PK/PD, animal translation, and resistance, keeping medicinal-chemist judgment and public-private funding central.