Jeremie Harris

Nathan Labenz × Prakash Narayanan × Jeremie Harris × Edouard Harris × Steve Hou × Joel Borgen × Daniel McKinnon

Trump-Xi contact could create an AI-crisis hotline, but without pre-vetted verification tools, an incident could trigger a demand to shut down a large cluster.Hyperscalers charge at least two to three times neo-cloud GPU prices; Gamo’s o3 loop found a 91-kilobase deletion, while Opus 5.5 scored about 50% on RareBench versus roughly 10% for LIRICAL.

Abhi Mahajan × Helen Toner × Jeremie Harris × @8teAPi × Nathan Labenz

The clearest near-term AI-biology opportunity is rescuing clinical value: Noetik combines pathology, 16-plex spatial proteomics, 19,000-gene spatial transcriptomics, and exome sequencing to find response biomarkers in trials where 97% of oncology candidates fail.Biology’s slow, ambiguous, expensive feedback makes rapid recursive improvement less likely, while AI-led R&D could still produce jagged acceleration; continuous risk measurement, infrastructure resilience, and the uncertain 2027–2030 horizon remain key variables.

Nathan Labenz × Jeremie Harris × Edouard Harris

Superintelligence could become a decisive national-security capability, but an intelligence explosion would create strategic advantage only if a country can reliably control or align the system.Racing China heightens loss-of-control risk, while slowing unilaterally could surrender leverage; meanwhile, data centers, ASPEED controllers, transformers, and TSMC-linked supply chains create attack paths before late-2026 or 2027 facilities are complete.The proposed answer is observability and credible deterrence rather than perfect defense, but secure governable chips and a near-term trust-and-verify regime remain unavailable.