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Dwarkesh Podcast · · 123 分钟

Michael Nielsen:为什么外星文明会拥有与我们不同的技术栈

Dwarkesh PatelMichael Nielsen

YouTube
TL;DR
  • Dwarkesh 带入节目的前提——AI 会像在编程领域那样,在科学上一路狂奔,因为两者都有紧密的验证闭环——正是本期要拆解的观点。 Nielsen 最有力的反例是 Prout 1815 年提出的假说:所有原子核的重量都是整数;氯的测量值先是35.5,随后更精确地变成35.46,反而离正确分数更远,而不是更近。人们花了85年才发现,同位素在化学上无法区分,这意味着在将近1个世纪里,验证闭环都在“主动排斥正确理论”。
  • Nielsen 对标志性 AI for Science 成果的重新定性,是整场对话里最值得交易的一句话:AlphaFold 真正的核心并不是 AI。 胜果建立在 Protein Data Bank 之上——X射线衍射、NMR、冷冻电镜,以及为获得约18万种结构投入的数十亿美元——之后“我们只是在最后拟合了一个漂亮的模型,而这只占整个投入的一小部分”。主导性投入是仪器化数据采集,而不是模型能力。
  • 瓶颈不会消失,只会迁移,而 Nielsen 认为这几乎是定义使然:你必然会在现有方法无法适用的地方遇到瓶颈。 他举了程序员朋友的实时案例:原型开发从3周缩短到3小时,但他们现在卡在如何提出有趣的设计想法上——“我们没有真正的验证闭环,来判断一个设计想法是否足够有趣”。
  • 对于一个参数量超过1亿的模型能否成为解释,Nielsen 提出3种理解,并认真对待第3种:这类模型可能是“一种新型对象”,可以像 Mathematica 处理方程那样被合并、蒸馏。 100页的方程过去意味着走进死胡同,如今却可能变成可操作的对象。Dwarkesh 的反驳很尖锐:如果用1500年的天空数据训练深度学习模型,它只会发现更多本轮,参数从X到Y编码下一个本轮——“我们还没有相应的动词”。
  • 边际收益递减可能是偶然形成的,而非内生属性。 Nielsen 用自助餐作比:静态情况下,最好吃的甜点确实会先被拿走;但他认为总有人持续补货。计算机科学就是数学哲学中一些晦涩问题的副产品,“边际收益递减论在那里面根本不成立”。针对 Bloom 发现摩尔定律每年40%的密度提升,需要半导体科学家数量每年增加9%,他的回应是这些指标刻意设得过窄;一个可能的突破口在制度层面,包括资本配置、人才培养,以及“让研究人员获得基本安全感,不必担心宗教裁判所”。
  • 反决定论的核心判断是:“技术树的大部分分支永远不会被探索。”深层想法太多,而探索者太少,所以方向选择确实重要。他把 DDT、含氯氟烃和《不扩散核武器条约》视为早期证据:制度可以提前决定“我们不走那条路”,这与技术发展不可避免的叙事正相反。
  • Dwarkesh 提出一个 Nielsen 之前没想过的观察:如果技术树具有路径依赖,那么遥远未来的文明之间会存在“巨大的贸易收益”,“这会让友好变得更有回报”。Nielsen 的保留意见是,思想传播成本低,产能却不会;比较优势只是“一个特殊且有限的模型”——“黑猩猩能做有趣的事情,但我们不会和它们贸易”。
  • 对任何资助研究的人而言,组合管理的教训是:同一种动作可能带来截然不同、事前无法预测的结果。天王星的轨道偏差在1846年带来了海王星;水星每世纪43角秒的偏差则带来了不存在的 Vulcan,最终需要广义相对论来解释。Nielsen 的规则是:“事前你无法判断哪一个才是该做的,实际上两件事都必须做。” Dwarkesh 又补充了一个基准概率:99.9%的异常都很平庸,比如 Pioneer 探测器的非对称热辐射。
摘要 · 为研究而整理的核心内容

1. Michelson-Morley 实验没有杀死以太——证伪从来不是教科书写的那回事

  • Nielsen 修正了 YouTube 版本的叙事:Michelson 和 Morley 做实验,是为了相互检验关于以太的不同理论,具体是在寻找以太风——光线顺着以太风传播会更快,逆着传播会更慢。他们没有发现以太风。这一结果“排除了部分以太理论,但不是全部”;当时的主流物理学家将其解读为:“这让我们获得了大量关于以太应当是什么的信息,但并不能说明以太不存在。”
  • 关键细节在于,失败理论的支持者坚持了多久。Michelson 在1881年完成第一次实验,Rayleigh 指出问题后于1887年重做;到了1920年代,他仍在进行以太实验,直到大约1929年去世前一直相信以太,甚至在去世前1到2年还公开发表过这一立场。
  • Miller 也没有停手。他登上 Mount Wilson,认为在更高海拔处,地球不会把以太风一并拖着走,并宣布自己测到了这一效应。Einstein 的回应是本期第一个精彩句子:“上帝深邃莫测,但并不怀有恶意。”
  • Nielsen 对方法论的判断保持了同样的谨慎:“这当然不能证明关于证伪的观念是错误的,或已经被证伪;但它确实说明,最朴素的那些想法……事情往往比你以为的复杂得多。” Dwarkesh 又补充说,连定冠词都暴露了问题——仅仅是那里用了“the”,其实就是误称。

2. 在实验更偏爱相对论之前,科学共同体已经倾向于它

  • Lorentz 在 Einstein 之前就得出了正确的参考系转换数学,但仍通过以太来解释:长度收缩和时间膨胀,是“穿过以太所产生的效应”;以太压力会“扭曲时钟”,也会扭曲长度测量。他所说的“地方时”并不是一个试图赋予物理意义的量;Nielsen 认为,Poincaré 更接近于意识到它其实就是时钟记录的时间。
  • 介子证据又过了40多年才出现。Nielsen 讲的是一个故事,而非一条数据:宇宙射线撞击大气层,产生介子;在经典假设下,介子的衰变速度太慢,根本无法在抵达地面前完成衰变。Nielsen 说,约1940年测得、可能于1941年发表的衰变率,与狭义相对论完全吻合。如果 Lorentz 当时还活着,“很可能会再次修补自己的理论,试图把它拯救出来”。
  • Dwarkesh 更谨慎地重述自己的观点:科学共同体“在实验真正显示哪种解释更优之前,就接受了我们事后认为更正确的解释”。Nielsen 立即打断了“过程”这个词:它“带有某种预先设定好的意味”,而事实上不存在中央权威,也不存在统一方法。Lorentz、Poincaré 和 Michelson 都是杰出科学家,却“始终没有与这一事实和解”。
  • Nielsen 留下的主线是:“伟大的科学家在科学共同体整体改变看法之后,仍可能长时间坚持错误。” 进步依然会发生,只是没有一个可以清晰表述的程序来解释它如何发生。

3. 专业知识也是牢笼——Poincaré 拥有前提,却仍然错过了结论

  • Nielsen 认为 Poincaré 的案例尤其惊人:他似乎已经拥有相对性原理,以及所有惯性系中的光速恒定——“基本上就是 Einstein 用来推导狭义相对论的那些想法”——但仍把长度收缩当成一种动力学效应,认为粒子受到外部力量而被推挤到一起,而不是纯粹的运动学现象。
  • Nielsen 说,在一篇发表于1909年的论文中,这种动力学图景依然存在,而诚实的答案是:“他为什么要抓住这个想法不放?我不知道。我显然从没见过这个人。” 录音室里给出的诊断是:“他几乎像是知道得太多了。他脑子里有一个过于宏大的愿景。” Einstein 的胜利,反而来自删减。
  • Nielsen 提出一个明确带有保留、且存在争议的猜测:Einstein 在1890年代还是少年时,也相信以太,但“他没有像那些年长者一样紧紧抓住它。也许他们有点成了自身专业知识的囚徒。这是我的猜测。一些科学史家当然会不同意。” Nielsen 还指出,Einstein 后来在量子力学和宇宙学上也扮演了类似角色。

4. 哥白尼既不更准确,也不更简单——真正具有说服力的是统一解释

  • Dwarkesh 对这一问题的铺垫,是检验科学品味的最好案例:托勒密模型更准确,因为经过数百年积累,它加入了大量本轮;而不太为人所知的是,哥白尼需要更多本轮,而不是更少,因为他坚持地球以匀速做完美圆周运动。“那么,你怎么可能在事前知道哥白尼是对的、托勒密是错的?”
  • Nielsen 给出的部分答案,是他认为有说服力的解释,而非对历史记录的复述:Newton 的万有引力同时解释了 Kepler 的行星运动、地球上抛掷物体的抛物线轨迹,以及月球和太阳对水体引力造成的潮汐。“看起来完全不同、彼此割裂的3种现象,竟然都由同一组思想解释。这开始让人觉得非常有说服力。”
  • Keynes 关于 Newton 的文章,为这种头脑提供了框架:“Newton 不是理性时代的第一个人,而是魔法师时代的最后一个人;他是最后一位伟大的思想家,他观察可见世界和思想世界时,所用的目光与那些不到1万年前开始构建我们知识遗产的人相同。” Keynes 还写道,Newton 的秘传研究显示出“疯狂中的极端方法性”,如果不考虑其全部内容和目的都带有魔法色彩,那么它们“与《原理》一样理智”。
  • Dwarkesh 将问题转化为真正的 AI 命题:曾帮助 Newton 和 Einstein 的简约性与审美判断,是否能够跨越时代和学科迁移?“即使我们无法为科学建立验证闭环,也许只要品味测试指向同一方向,至少可以把这种偏向编码进 AI。”

5. 瓶颈会按定义迁移到方法失效的地方

  • Nielsen 对“把品味编码进去”这一希望的回答是结构性的:“如果你试图把科学还原成一个过程,你就是在试图把它还原成某种可以套用的方法:转动曲柄,洞见就会自己蹦出来。你确实可以做到一部分,但最终一定会在现有方法无法适用的地方遇到瓶颈。按定义,这里没有曲柄可转。”
  • 因为人们研究那些已经被证明有效的东西,所以不会在前人曾经卡住的地方继续卡住——“他们会在不同的地方不断遇到瓶颈”。一个想法越难,堵塞的规模越大,最终的回报也越大:“瓶颈越大,胜利也越大。”
  • Dwarkesh 给这个理论提出了一个难题:《Principia》发表于1687年,《物种起源》发表于1859年,而 Huxley 对 Darwin 的反应是:“这么愚蠢的事情,怎么之前没人想到?” 但没有人读《Principia》时会想,自己本可以抢在 Newton 之前想到它。Nielsen 认为,Darwin 的天才不在于提出这个想法——动物育种者早已知道人工选择——而在于“理解它对生物学究竟有多核心”,并完成把它与地质学及其他一切连接起来的艰苦工作。
  • 这正是验证闭环差异的体现:Newton 可以检验月球轨道周期和潮汐;但对 Darwin 来说,“没有任何一个单独事实具有压倒性力量”,而且他没有机制、没有基因。Dwarkesh 提到的时间线——1830年代 Lyell 提出的深时观、古生物学、殖民时代带来的生物地理学,以及 Wallace 几乎同时寄来的论文——说明这些积木都是必要条件。“Darwin 的反应是:‘操。’我不认为这是逐字引用,但基本准确。” Nielsen 同意深时观是承重结构:如果采用 Ussher 的6,000年时间尺度,就必须假设进化在人的一生中以极高速度发生,但现实中完全看不到这种现象。

6. AlphaFold 是一场披着 AI 外衣的数据采集工程

  • Nielsen 用非常平淡的语气说出一个足以让人重新思考“闭合发现的强化学习循环”的事实:“到目前为止最大的标志性成功,当然是 AlphaFold。但 AlphaFold 真正的核心并不是 AI。” 其中绝大部分成功来自 Protein Data Bank:X射线衍射、NMR、冷冻电镜,以及为获得约18万种蛋白质结构投入的数十亿美元。
  • 对任何承保 AI for Science 的人而言,顺序很重要:“我们花了几十年时间,通过极其仔细地观察现实世界来获得蛋白质结构,然后在最后拟合了一个漂亮的模型,而这只占全部投入的一小部分。” Nielsen 认为 AI 部分“非常令人印象深刻,也非常非凡”,但它只是整个故事的一小部分。
  • 他并不是要因此否定成果——结构生物学家“似乎认为 AlphaFold 是一次巨大的进步。这是一个冲击”。他真正提出的问题更窄,也更准确:“我们主要卡在某一种事情上,还是同时卡在多种事情上?”

7. 训练出来的模型是解释吗?3种答案,以及“我们还没有相应的动词”

  • Dwarkesh 将问题推向下一个层面:广义相对论最终归结为方程,并能预测它从未被用来解释的现象,比如水星近日点进动;而 AlphaFold“把我们甚至无法通过超过1亿参数解读的各种关系编码在一起”。这两者真的是同一种东西吗?Nielsen 称其为“可能极其关键的问题”。
  • 第一个答案最保守:人们希望用尽可能少的自由参数、尽可能简单的模型解释尽可能多的现象,因此 AlphaFold“作为模型很漂亮,也可能有用,但它不是科学解释”。第二个答案是,它内部包含许多微型解释,可以通过可解释性研究进行“AlphaFold 考古”并提取出来。他举的先例是 Magnus Carlsen 似乎在 AlphaZero 被公开分析后改变了自己的棋风,但“我不认为有任何公开确认”。
  • 第三个答案是 Nielsen 最感兴趣的:模型是“一种新型对象”,应该认真把它们当作解释,因为现在“我们可以合并它们,也可以蒸馏它们”。他想到的是 Mathematica:1920年,一条100页的方程意味着你只能放弃;而今天,“它已经成为一个对象,一个你可以操作的东西”,有时最后还能得到简单答案。
  • Dwarkesh 的反驳是整场对话中最有力的一刻:在1500年,用天空观测数据训练一个深度学习模型,再对它进行解释,“你只会不断在托勒密模型上继续加东西……参数X到Y编码下一个本轮”。蒸馏可以在局部降低误差,但哥白尼式转向在全局上更优、在局部上却更差——“如果只是原始梯度下降,我不太觉得它会做到这一点。” 他的总结是:“我们还没有相应的动词。” Nielsen 的回应则提出了强制性条件:Einstein 立刻看出,牛顿式超距作用加上狭义相对论会允许超光速传信,而“意识到这里存在一个大问题,并不需要太大的飞跃”。

8. 验证闭环可能敌视正确答案85年——所以每条研究路线都要保留

  • Nielsen 的成对案例,是支持研究组合广度的最清晰论证:天王星偏离预测位置,带来了海王星——“这是 Newton 万有引力的辉煌、巨大的成功”;水星偏离预测位置——Dwarkesh 提供了每世纪43角秒——却带来了并不存在的 Vulcan。“你追求的是非常相似的想法,但一个案例极其成功,另一个则彻底、完全失败。事前你无法判断哪一个才是该做的,实际上两件事都必须做。”
  • Dwarkesh 详细说明了一个坚定的牛顿主义者会如何继续拯救理论:宇宙尘埃遮住了行星;行星太小、看不见;造一台更大的望远镜;或者磁场破坏了测量。Nielsen 举了1990年代 Pioneer 探测器的版本:探测器轨道略有偏差,你可以兴奋地认为广义相对论错了,但最终被接受的答案是非对称热辐射产生了一个指向太阳的微小加速度。
  • 基准概率才是结论,而且它与这些故事通常的讲法相反:“99.9%的时候,最后都只是某种类似这种热加速度的效应……遗憾的是,这些故事里有大量选择偏差。” Dwarkesh 又补充说:“不存在任何事前启发式,能告诉你自己处于哪一种情况。”
  • Prout 是 Lakatos 意义上的极端案例。1815年,一位化学家提出所有原子核的重量都是整数;氯测得35.5;当更好的测量给出35.46时,这个半整数修补方案反而离正确分数更远,而不是更近。85年后,人们发现同位素在物理上可以区分、但在化学上无法区分。“你只需要这个残余现象来支撑理论……事前没有理由认为它就是更优理论。”

9. 技术树巨大,边际收益递减可能是偶然的,而大多数分支永远不会有人走上去

  • Nielsen 用计算机科学来激发直觉:它在1930年代已经拥有“万物理论”,此后却花了“90多年探索其后果”。公钥密码学“极其深刻,非常不显然”,早在1930年代就已经潜藏其中,而其内部又包含了加密货币和集体维护账本背后的思想。Knuth 的轶事则完成了封口:有人让他“等有1,000个深刻定理时再回来”,几十年后他指出,“现在显然已经有1,000个深刻定理了”。
  • 物态也说明了同一件事:学校里通常只讲3种,有时讲4种或5种;但后来又有超导体、超流体、玻色—爱因斯坦凝聚态、量子霍尔体系和分数量子霍尔体系——“在某种意义上,我们将开始能够设计它们”。他对探索者的自评是:“我们基本上只是稍微进化了一点的黑猩猩,所以动作很慢,需要时间。”
  • 面对 Dwarkesh 基于 Bloom 的挑战——摩尔定律带来晶体管密度每年40%的增长,同时要求半导体科学家数量每年增加9%,而且这一规律在一个又一个行业中得到复制——Nielsen 先攻击了问题的框架:“他们举的所有例子都很窄……那里根本没有 GPU。” 但他承认这一现象可能真实存在,并指出外部条件可能是原因之一:1700年以前的进步缓慢而不规律,部分原因在于“思想周围需要制度”,包括人才训练、资本配置,以及“让研究人员获得基本安全感,不必担心宗教裁判所”。甜点自助餐会不断补货,这正是新领域能让21岁年轻人取得突破的原因。
  • 他最坚定、也最有后果的结论是:“技术树的大部分分支永远不会被探索。” 等待发现的深层想法太多,不仅是我们,任何文明都不可能发现其中的大多数。因此他反感技术决定论,并认为 DDT、含氯氟烃和《不扩散核武器条约》都是塑造分支选择的制度。Dwarkesh 进一步推论,路径依赖的技术树意味着文明之间在遥远未来存在贸易收益,因此“会让友好变得更有回报”。Nielsen 回应:“我完全没想过这一点。” 但他也指出边界:思想传播便宜,制造能力不会;“黑猩猩能做有趣的事情,但我们不会和它们贸易。” Dwarkesh 自己的保留意见是,比较优势并不保证贸易条件高于生存线:我们不会让马继续走在道路上,而在旧金山养一匹马,每年花费10万美元也不值得。

10. 学科是在条件成熟时打开的,不是在天才出现时打开的

  • 当被问到为什么量子计算在1950年代还不存在——von Neumann 既开创了计算学,又写过量子力学领域的重要著作——Nielsen 给出的答案刻意保持平庸:两件互不相关的事情在1980年前后同时成熟。计算变得切实可感,是因为“你可以买一台 Apple II,也可以买一台 Commodore 64”;而 Paul trap 则首次让人们能够捕获单个离子、操纵单个量子态。
  • 他留下的画面是:Feynman 在1980年或1981年前后拿到第一批个人电脑之一,“显然兴奋到了极点,抱着这台全新的计算设备走路时,竟然绊倒并严重受伤”。一个在量子力学上如此有天赋的人,恰好又对这些机器如此兴奋,这是“一个非常依赖历史偶然性的巧合……10年前你能讲出什么类似的故事?那些条件根本不存在。”
  • 他自己的入行经历,是后续市场如何形成的第一人称版本。“1985年我11岁。我根本没想这些。我在踢足球。” 1992年,他上了 Gerard Milburn 的量子力学课程,开口索要论文,拿到“一大摞”材料,其中包括 Deutsch 和 Feynman 的论文;当时全世界基本没人研究这个方向。“在某种意义上,我受益于另一个人的品味。” 真正吸引他的是 Deutsch 的猜想:量子图灵机可以高效模拟任何物理系统——“我觉得他在那篇论文里基本上声称自己已经证明了这一点,但我不确定所有人都会同意。”
  • 对量子计算的上限,他拒绝接受 Dwarkesh 的紧边界:“我们只思考了它大约40年……作为一个文明,我们还没有认真思考过它。” 更关键的是,“我们一直在没有设备的帮助下研究它。这是一个相当大的瓶颈。” 他提出一个明确标注为推测的设想:可能会先经历一段运行在经典计算机上的 AGI 时代,随后进入量子机器上的 AQGI 时代,“很可能能够完成严格更大类别的潜在有趣计算”。

11. 归因经济是被发明出来的,真正的瓶颈在于你如何学习

  • Nielsen 认为,开放科学的胜利在于 Dwarkesh 不需要先定义它;20年前,他可能必须这么做。更深层的问题是,信用本身是被构造出来的:3个世纪前,Galileo 和 Kepler 有时会把研究成果写成打乱顺序的字谜,留待日后解开,以此主张优先权——“这不是发现系统的理想基础”。人类花了超过1个世纪,才发展出论文、归因和声誉经济。如今,代码、数据和进行中的想法都可以在没有信用归属的情况下共享。
  • 他最喜欢的例子说明,这完全是社会建构:生物学家告诉他,“生物学的竞争远比物理学激烈,我们必须保护优先权,所以绝不可能上传到预印本库”;物理学家却告诉他,“物理学的竞争远比生物学激烈,我们必须尽快上传到预印本库,以确立优先权”。“任何试图改变这种经济的做法,都会产生另一套构建知识的系统。”
  • 关于产出数量,Dwarkesh 引用 Dean Keith Simonton 的等概率法则:任何一篇论文或一本书产生影响的概率大致相同,因此生产力就是发表数量;“Shakespeare 只是发表了很多东西”。Gödel 则是反例,他“几乎什么都没发表”。Nielsen 将工作拆成两类:常规工作,要尽快做好、外包,不要拖延;高方差工作,则要愿意投入时间并接受失败。他也承认自己的账本:“有时我觉得自己太慢了。” 他想写的一本书,是“关于那些才华横溢却差一点成功的人,写出大量传记”——比如曾拿到 IMO 金牌、后来试图成为数学家却失败的人,因为“很多时候,这比其他任何东西都更有信息量”。
  • 最后的心理治疗式收束,是全场最实用的一段。Nielsen 会对没有解出问题的学生追问:“如果这里有100万美元,你会投入同样的努力吗?” 而答案总是不会。“他们尝试过,但并没有真正尝试。” Dwarkesh 对自己工作的诊断是,AI 节目有一个强制函数——把 Transformer 实现出来,就等于把某些东西钉死;历史节目却没有。卡住本身才是机制:几天写完的文章什么也没教会他,而花3个月写的文章,15年后他仍然记得。Nielsen 最后借 Alan Kay 评价 Linux 的话提醒 LLM 的风险:“它只是一个巨大的一团泥巴。” 因为“对于某类头脑来说,学习系统本身具有诱惑力,很容易把这种学习与理解混为一谈”。
Dwarkesh Patel

Today, I’m speaking with Michael Nielsen. You have done many things. You’re one of the pioneers of quantum computing, wrote the main textbook in the field of the open science movement, and wrote a book about deep learning that Chris Olah and Greg Brockman credit with getting them into the field. More recently, you’re a research fellow at the Astera Institute and writing a book about religion, science, and technology. I’m going to ask you about none of those things.

The conversation I want to have today is: How do we recognize scientific progress? It’s especially relevant for AI because people are trying to close the RL verification loop on scientific discovery. What does it mean to close that loop? But in preparing for this interview, I’ve realized that it’s a more mysterious and elusive force, even in the history of human science, than I understood.

I think a good place to start will be Michelson–Morley and how special relativity was discovered, if it’s different from the story that you get off of YouTube videos. I will prompt you that way, and then we’ll go in there.

Michael Nielsen

Michelson–Morley is the famous result often presented as this experiment that was done in the 1880s that helped Einstein come up with the special theory of relativity a little bit later, changing the way we think about space and time and our fundamental conception of those things. And there’s a big gap, I think, between the way Michelson and Morley and other people at the time thought about the experiment and certainly the way in which Einstein thought—or did not think—about the experiment.

In actual fact, he stated later in his life that he wasn’t even sure whether he was aware of the paper at the time. There’s a lot of evidence that he probably was aware of the paper at the time, but it actually wasn’t dispositive for his thinking at all. Something else completely was going on.

What Michelson and Morley thought they were doing was testing different theories of what was called the ether. If you go back to the 1600s, Robert Boyle introduced the idea of the ether. We know that sound is vibrations in the air. Boyle and other people got interested in the question of whether light is vibrations in something, and they couldn’t figure out what it was.

Boyle did an experiment where he tested whether you could propagate light through a vacuum. He found that you could. You couldn’t do it with sound. He introduced this idea of the ether, and for the next 200 or so years, people had all these conversations about what the ether was and what its nature was.

The Michelson–Morley experiment was really an experiment to test different theories of the ether against one another, in particular to find out whether or not there was a so-called ether wind. The idea was that the Earth is maybe passing through this ether wind. If it is passing through the ether wind and you shoot a light beam parallel to the direction the ether wind is going in, it’ll get accelerated a little bit. If it’s being passed back in the opposite direction, it’ll get slowed down a little bit, and you should be able to see this in the results of interference experiments.

What they found, much to their surprise, was that in fact there was no ether wind. That ruled out some theories of the ether, but not all, and Michelson certainly continued to believe in the ether.

Dwarkesh Patel

This was the shocking part of reading this story from the biography of Einstein that you recommended by—what was his first name?

Michael Nielsen

Abraham Pais.

Dwarkesh Patel

Abraham Pais. Subtle Is the Lord. Also from Imre Lakatos’s The Methodology of Scientific Research Programmes, the way it’s told is that Michelson–Morley proved that the ether did not exist. Therefore, it created a crisis in physics that Einstein solved with special relativity.

What you’re pointing out is that he was actually trying to distinguish between many different theories of the ether.

Michael Nielsen

If you’re in space or if you’re on Earth, it’s the same direction of ether, or maybe the ether wind is being carried around by the Earth, and so you can’t really experience it on Earth. But if you go to a high enough altitude, you might be able to experience it.

In fact, Michelson’s experiments—the famous one is in 1887, but he conducted these experiments for basically 2 decades. For longer than that. He conducted the first one in 1881, I think, but he continued to believe until he died. He died, I think, in 1929 or so. It was the late twenties. He was still doing experiments in the 1920s about whether or not the ether existed.

So he continued to believe in the ether to the end of his life. I think the last public statement he made was a year or 2 before he died, and he basically still believed it at that point.

In fact, there was another physicist, Miller, who kept doing these experiments in the 1920s. He thought that if he went to a high enough altitude—Mount Wilson in California—he would be high enough that the ether winds were not being dragged by the Earth, and he had measured the effect of the ether.

Einstein hears about this and he says—and this is where you get the famous quote—“Subtle is the Lord, but malicious He is not.”

Dwarkesh Patel

Anyway, I think the reason the story is interesting is for many different reasons. One of the ways in which the real history of science is different from this idea you get of the scientific method is that you really can’t apply falsification as easily as you might think. It’s not clear what is being falsified. Is it just another version of the theory of the ether that’s being falsified?

Certainly, you can’t induce the theory of special relativity from the fact that one version of the ether seems to be disconfirmed by these experiments. It certainly doesn’t show that ideas about falsification are wrong or falsified, but it does show that the most naive ideas are often much more complicated than you think.

Michelson did this experiment in 1881. He was a very young man, and then other people—I think Rayleigh was one of them—pointed out that there were some problems with the way he did it, so they had to redo it in 1887. At that point, a lot of the leading physicists of the day basically accepted this result, that there was no ether wind.

But what to do about this? Sure, maybe you falsified some theories of the ether. There are others that you haven’t falsified at all at this point, and people set to work on developing those. It is funny: people will phrase it as showing that the ether didn’t exist. Even just the word “the” there is a misnomer. You actually had a ton of different theories and a couple of leading contenders.

So yes, there’s some version of falsification going on, but how you respond to this new experiment is very complicated.

Michael Nielsen

Certainly, the leading physicists of the day responded by saying, “Okay, this gives us a lot of information about what the ether must be, but it doesn’t tell us that there is no ether.”

In fact, Lorentz, at the end of the 19th century, before Einstein, figures out the math of how you convert from one reference frame to another reference frame and comes up with the Lorentz transformations, which are the basis of special relativity. But his interpretation is that you are converting from the ether reference frame to these non-privileged other reference frames if you’re moving relative to the ether.

His interpretation of length contraction and time dilation is that this is the effect of moving through the ether, and you have this pressure. This pressure is warping clocks. It’s warping measures of length.

The interesting thing here is that experimentally you cannot distinguish Lorentz’s interpretation from special relativity.

Dwarkesh Patel

I think that’s a strong statement.

Michael Nielsen

Lorentz introduces this quantity called local time.

Dwarkesh Patel

My understanding is that he’s not trying to give a physical interpretation of this, but it’s what Einstein would later just recognize as time in another inertial reference frame.

Michael Nielsen

He’s not trying to attribute much physical meaning to it. I think Poincaré gets much closer later on to realizing that this is the time that’s registered by clocks.

About 40-odd years later, people start doing these muon experiments where they see cosmic rays hit the top of the atmosphere. They produce a shower of muons, and you can look to see at different heights in the atmosphere how many of those muons remain. They decay over time, and a very strange thing happens, which is that they’re decaying way too slowly.

You expect they shouldn’t be able to last the whole way through the atmosphere at all. Their decay rate is too quick if you were in a classical theory. But if in fact their time really has slowed down, it’s okay.

In fact, the measured decay rates in 1940—and there have since been more accurate experiments done—match exactly what you expect from special relativity. That’s the kind of thing where, if Lorentz had been alive—he’d been dead 10 or so years at that point—it seems quite likely that he would have tried to save his theory by patching it up yet again, but it would have been a massive setback.

It starts to just look like time—this thing that Lorentz introduced as a mathematical convenience—that's actually what time is, for the muons at least. Then there's a whole bunch of other experiments that show this very similar phenomenon.

Dwarkesh Patel

When was that experiment done?

Michael Nielsen

That was, I think, 1940. It might have been published in 1941. Maybe to rephrase and change my claim: it's not that you could not have distinguished them, but the scientific community adopted what we, in retrospect, consider the more correct interpretation before it was actually experimentally shown to be preferred. So there's clearly some process that human science uses to distinguish different theories.

Dwarkesh Patel

Can I just interrupt? You used the word “process,” and it's interesting to think about that term. Process carries connotations of something set in advance. It's much more complicated in practice. You have people like Lorentz, whom Einstein absolutely and utterly admired, and Poincaré, one of the greatest scientists who ever lived, and Michelson, another truly outstanding scientist, who never reconciled themselves.

It's not as though there's some standard procedure that we're all using to reconcile these things. Great scientists can remain wrong for a very long time after the scientific community has broadly changed its opinion. But there's no centralized authority or centralized method. That is the interesting thing.

Michael Nielsen

There's progress even though it is hard to articulate the process by which it happens—the heuristics that are used.

Dwarkesh Patel

You mentioned Poincaré. Lorentz has the math right, but the interpretation wrong. It seems like Poincaré had the opposite, where he understood that it's hard to define simultaneity because it requires a circular definition with time, or the velocity of something that might arrive at a midpoint together, but velocity is defined in terms of time.

I find this interesting. There are a couple of other examples we could call on. There is this phenomenon in the history of science where somebody asks the right question, but then they don't clinch it. I'm curious what you think is happening in those cases.

Michael Nielsen

You actually do want to go case by case and try to understand. It's not necessarily clear that they're doing the same thing wrong in all of the cases.

The Poincaré case is amazing. He seems to have understood the principle of relativity, the idea that the laws of physics are the same in all inertial reference frames. He seems to have understood that the speed of light is the same in all inertial reference frames. He doesn't phrase it quite that way, but it is my understanding, though I don't speak French.

These are basically the ideas that Einstein uses to deduce special relativity. But then he also has this additional misunderstanding where he thinks that length contraction is a dynamical effect, that somehow particles are being pushed together by some external force, that something is going on dynamically. He doesn't understand that it's purely kinematics.

That actually space and time are different from what we thought, and you need to fundamentally rethink those things. It's almost like he knew too much. He had almost too grand a vision in mind. Einstein subtracts from that and says, “No. Space and time are just different than what we thought, and here's the correct picture.”

There's a paper in—I think it's 1909—where Poincaré still has this dynamical picture of what's going on with the length contraction. This is just not necessary. This is a mistake from the modern point of view. Why is he doing this? Why is he clinging onto this idea? I don't know. I've obviously never met the man. It would be fascinating to be able to talk it over and try to understand.

His expertise seems to be getting in the way. He knows so much, he understands so much, and then he's not able to let go of these things. A really interesting fact is that a few years prior, in the 1890s, Einstein's a teenager and he believes in the ether too. He knows about this stuff. But he's not quite as attached as these older people were.

Maybe they were a little bit prisoners of their own expertise. That's my guess. Some historians of science would certainly disagree. Then there's the obvious stories where Einstein himself later on is said to have not latched onto the correct interpretations of quantum mechanics or cosmology because of his own attachments.

Dwarkesh Patel

Yeah. Here’s the bigger question I have. The muon example is a great example of these long verification loops and how progress seems to happen in the scientific community faster than these verification loops imply.

Maybe the clearest example is Aristarchus in the 2nd century BC, who comes up with the idea of heliocentrism. The ancient Athenians dismiss it on the grounds that we should see, as the Earth is moving around the Sun, the stars move relative to the Earth if the Sun is really the center of the solar system. The only reason that would not be the case is that the stars are so far away that you would not observe this.

And it's only in 1838 that stellar parallax was actually measured. And so, we didn't need to wait until 1838 to have heliocentrism. We didn't need to wait for the experimental validation to understand that Copernicus is better in some way.

In fact, when Copernicus first came up with his theories, it's well known that the Ptolemaic model was more accurate because it had centuries of adding on these epicycles. What's maybe less well appreciated is that it was also in some sense simpler.

Because Copernicus actually had to add extra epicycles. It had more epicycles than the Ptolemaic model because he had this bias that the Earth should go in a perfect circle in equal time. Anyway, I think this is an interesting story because it's not a more accurate theory. It's not a simpler theory. So how could you have known ex ante that Copernicus was correct and Ptolemy was not?

Michael Nielsen

Good question. I don't entirely know the answer. I can give you a partial answer that I, centuries in the future, start to find very compelling. I'm sure it's part of the historic story, at least.

One of the big shocks for Newton—he did understand Kepler's laws of motion eventually, so you're able to explain the motions of the planets in the sky. But he also, out of the same theory, his theory of gravitation, was able to explain terrestrial motion.

He's able to explain why objects move in parabolas on the Earth, and he's able to explain the tides in terms of the moon and the Sun's gravitational effect on water on the Earth. You have what seem like 3 very different, disconnected phenomena all being explained by this one set of ideas. That starts to feel very compelling, at least to me. I think most people find that very satisfying once they eventually realize it.

Dwarkesh Patel

Have you read the Keynes biography of Newton?

Michael Nielsen

He wrote an entire biography?

Dwarkesh Patel

No, the essay.

Michael Nielsen

Sure. I love that.

1. Newton was the last of the magicians

Dwarkesh Patel

This description of him as “the last of the magicians” is wonderful. In fact, I think it's maybe worth superimposing. Or you should read out that one passage of the thing.

Michael Nielsen

All right. It's from a talk that he gave at Cambridge not long before he died. He'd acquired Newton's papers somehow and gave a lecture twice about this, or his brother Geoffrey gave it the other time because he was too ill.

There's this wonderful, wonderful quote in the middle. The whole thing is really interesting, but I love this particular quote:

“Newton was not the first of the age of reason. He was the last of the magicians, the last great mind which looked out on the visible and intellectual world with the same eyes as those who began to build our intellectual inheritance rather less than 10,000 years ago.”

Dwarkesh Patel

This idea people have that Newton was the first modern scientist is somehow wrong. There's some truth to it, but he really had this very different way of looking at the world that was part superstitious and part modern. It was a funny hybrid. He's a transitional figure in some sense.

That phrase, “the last of the magicians,” really points at something. The thing I'm very curious about with Newton is whether it was the same program, the same heuristics, the same biases that he applied to his alchemical work as he did to his understanding of astronomy.

Michael Nielsen

This is from the Keynes essay:

“There was extreme method in his madness. All his unpublished works on esoteric and theological matters are marked by careful learning, accurate method, and extreme sobriety of statement. They are just as sane as the Principia if their subject matter and purpose were not magical. They were nearly all composed during the same 25 years of his mathematical studies.”

Dwarkesh Patel

Clearly, there was some aesthetic that motivated people like Einstein to reject earlier ways of thinking and say, “No, the ether is wrong, and there's a better way to think about things.” The same is true with Newton.

The question I have is whether similar heuristics toward parsimony, aesthetics, and so on would be equally useful across time and across disciplines, or whether you need different heuristics. The reason that's relevant is that even if we can't build a verification loop for science, maybe if the taste tests point in the same direction, you can at least encode that bias into the AIs. That would maybe be enough.

Michael Nielsen

The point is that where we always get bottlenecked is where the previous processes and heuristics don't apply. That's almost definitionally what causes the bottlenecks. Because people are smart, they know what has worked before. They study it. They apply the same kinds of things, so they don't get stuck in the same places as before. They keep getting bottlenecked in different places. I'm overgeneralizing a bit, but I think it's right.

If you're attempting to reduce science to a process, you're attempting to reduce it to something where there is just a method which you can apply, and you turn the crank and out pops insight. You can do a certain amount of that, but you're going to get bottlenecked at the places where your existing method doesn't apply. Definitionally, there's no crank you can turn.

You need a lot of people trying different ideas. The more difficult the idea is to have, the greater the bottleneck, but then also the greater the triumph. Quantum mechanics is a great example of this. It's such a shocking set of ideas. It's such a shocking theory. The theory of evolution, in some sense, is also quite a shocking idea—not the principle of natural selection, but that it can explain so much. That's a shocking idea.

2. Why wasn’t natural selection obvious much earlier?

Dwarkesh Patel

So the Principia is released in 1687. On the Origin of Species is released in 1859. At least naively, it seems like Darwin's theory of natural selection is conceptually easier than the theory of gravity. I asked Terence Tao this question.

There was this contemporaneous biologist with Darwin, Thomas Huxley, who read this and said, “How extremely stupid to not have thought of this.” Nobody ever reads the Principia and thinks, “God, why didn't I beat Newton to the punch here?” So what's going on here? Why did Darwinism take so much longer?

Michael Nielsen

The idea must have been known to animal breeders for a long time at some level, or certainly large chunks of the idea were known, that artificial selection was a thing. In some sense, Darwin's genius wasn't in having that idea; it was understanding just how central it was to biology. You can go back and explain a tremendous amount about all the variety of what we see in the world with this as not necessarily the only principle, but certainly a core principle.

He writes this wonderful book, On the Origin of Species. It's just so much evidence and so many examples, trying to tease this out and see what the implications are, and connecting it to as much else as he possibly can—to geology and all these other things. That hard work—making the case that it's actually relevant all across the biosphere—is what he's doing there. He's not just having the idea; he's making a compelling case that it's intertwined with absolutely everything else.

Dwarkesh Patel

The motivation for the question was Lucretius, this 1st-century Roman poet who has an idea that seems analogous to natural selection. It's about species getting fitted more over time to their environments, or species losing fit to their environment. And so, why did this go nowhere for 19 centuries? Then I looked into it—or, more accurately, asked LLMs what exactly Lucretius's idea here was.

Michael Nielsen

It is extremely different from what real natural selection is. He thought there was this generative period in the past where all the species came about, and then there was this one-time filter which resulted in the species that are around today, and they became fit to the environment. He did not have this idea that it is an ongoing gradual process or that there is a tree of life that connects all life forms on Earth together, which, by the way, is an incredibly weird fact: that every single life form on Earth has a common ancestor.

Dwarkesh Patel

It's not incredibly weird. If you think that the origin of life must have been very hard, that there's a bottleneck there, then it's not so surprising. There's also this verification loop aspect where even if Newton might be harder in some sense, if you've clinched it, you can experimentally validate it—I know “validate” is the wrong word philosophically—but you can give a lot of base points to the theory.

You can be like, “Okay, I have this idea of why things fall on Earth. I have this idea of why orbital periods for planets have a certain pattern. Let's try it on the Moon, which orbits the Earth.” And in fact, it's weird, but the orbital period matches what my calculations imply. And the tides work correctly. It's just amazing.

Michael Nielsen

Exactly. Whereas for Darwinism, it takes a ton of work for Darwin to compile all the cumulative evidence, but there's no individual piece that is overwhelmingly powerful. And there's a whole bunch of problems as well. He doesn't really understand what the mechanism is. He doesn't understand genes, all these things.

The very interesting thing in the history of Darwinism is this idea which, theoretically, you could come up with at any time. There is almost identical independent creation of that idea between Alfred Wallace and Charles Darwin. So much so that I think Wallace sends his manuscript to Darwin and is like, “What do you think of this idea?” And Darwin's like, “Fuck.” I don't think that's an exact quote, but it's pretty much correct. They end up presenting their ideas together in the spirit of sportsmanship.

Dwarkesh Patel

Why was this period in the 1850s or 1860s the right time for these ideas to form?

Michael Nielsen

You can come up with different ideas. One is geology. In the 1830s, Charles Lyell figures out that there have been millions and billions of years of time on Earth. Paleontology shows you that fossils have existed for that entire time. Life goes back a long way. In fact, you can even find fossils for intermediate species that show you the tree of life. Between humans and other apes as well, there are intermediate humans.

There's also the age of colonization, and we have all these voyages doing biogeography. That all must have been necessary.

Dwarkesh Patel

In fact, there's a huge history of parallel innovation and discovery in the history of science. So maybe it is another piece of evidence that more had to be in place for a given idea to be discovered. Because if it's not discovered for a long time and then spontaneously many different people are coming up with it, that shows you that the building blocks were in some sense necessary.

Michael Nielsen

This example of Lyell and other geologists in the early 1800s having this idea of deep time does seem to have been crucial. I know Darwin was very influenced by Lyell. If you don't have at least tens or hundreds of millions of years, evolution starts to look like a non-starter.

In order to make it work on a timescale of 5,000 to 10,000 years—or 6,000 years with Bishop Ussher—you would need to see evolution occurring at a massive rate during human lifetimes, and we're just not seeing that. That does seem to have been a blocker. To your question of what other blockers were there—were there any others? I don't know.

3. Could gradient descent have discovered general relativity?

Dwarkesh Patel

Or how much earlier could you, in principle, have come up with it if you were much smarter? Let's go back and zoom out to your original question about the verification loop in AI. An example that should give you pause there is the big signature success so far, which is certainly AlphaFold.

Michael Nielsen

AlphaFold really isn't about AI. A massive fraction of the success there is the Protein Data Bank. It's X-ray diffraction, NMR, cryo-EM, and the several billion dollars that were spent obtaining those 180,000-odd protein structures. It's basically the story of how we spent many decades obtaining protein structure just by going out and looking very hard at the world experimentally, and then we fitted a nice model at the end of it, which was a tiny fraction of the entire investment. That's a story of data acquisition principally. The AI bit is very impressive and quite remarkable, but it is only a small part of the total story.

Dwarkesh Patel

AlphaFold is very interesting, and philosophically I wonder what you think of it as a scientific theory or explanation. I guess over time the world is becoming harder to understand. As I'm saying things, because you're such a careful speaker, I say a phrase and wonder if you'll actually buy that premise. But in some domains, we need to fit models to things rather than coming up with underlying principles that explain a broad range of phenomena.

Compare the theory of general relativity, or any theory which just nets out to some equations, versus AlphaFold, which is encoding these different relationships between things we can't even interpret over 100 million parameters. Are those really the same thing? GR can predict things you could have never anticipated or that it was never meant to do, like why Mercury's orbit precesses. AlphaFold is not going to have that kind of explanatory reach. I want to get your reaction to that.

Michael Nielsen

I think it's an incredibly interesting question. Maybe a really pivotal question. If you take a very classic point of view, you want these deep explanatory principles. You want as few free parameters as you possibly can. You want very simple models which explain a lot, and AlphaFold doesn't look anything like that. You might just say, “It's nice and maybe helpful as a model, but it's not a scientific explanation.” That's a conservative point of view, answer one to the question.

Answer two is to say maybe you shouldn't think about AlphaFold as an explanation in the classic sense, but maybe it contains lots of little explanations inside it. Part of what you can get out of interpretability work is you can go into AlphaFold and start to extract certain things. Maybe by doing an archaeology of AlphaFold, we can actually understand a great deal more about these principles. You can start to extract that a certain circuit does this interesting thing, and we learn from it.

I don't know to what extent that's been done with AlphaFold, but it's been done a little bit with some of the chess models, like AlphaZero. There seem to be some strategies which were borrowed by Magnus Carlsen, which he seems to have just taken from AlphaZero. I don't think there's any public confirmation of this, but some experts have noticed that he changed his game quite radically after some public forensics were released on how AlphaZero worked. That's an example where human beings are starting to extract meaning out of these models. That leads to viewing the models as a potential source of explanations. You need to do more work because they're not very legible up front, but you can potentially extract them.

That's an interesting intermediate situation where they're not explanations themselves, but you can extract interesting explanations out of them and use them as a source. The third and most interesting possibility is that they're a new type of object. They should be taken very seriously as explanations, but where in the past we haven't had the ability to really do anything with them, now we have interesting new actions we can do. We can merge them, we can distill them. It's a big opportunity in the philosophy of science.

There's an anticipation of this in some way. Some mathematicians and physicists work today with these things. Historically, if you had a 100-page equation—which is the kind of thing that does come up—there's just nothing you can do if it's 1920. At that point, you give up on the problem. But today, with tools like Mathematica, you can just keep going. That's an object now, a thing that you can work with.

There are examples where people work with these things that formerly were regarded as too complicated, and sometimes they get simple answers out the end. That's just an intermediate working state. So I wonder if something similar is going to happen in this case, where you could take these models and use them in a similar way that people do with Mathematica, and take them seriously. They're not explanations in the classic sense, but they'll be something else which interesting operations can be done on.

Dwarkesh Patel

The thing I worry about is this: suppose it's 1500 and you're training a model. This is a weird history where we developed deep learning before we had cosmology. Suppose we live in that world. You're observing how the stars don't seem to move. The planets have all these weird behaviors. Then you train a model on that, and you do some kind of interpretability on it, trying to figure out what the patterns are. You'd just be able to keep building on Ptolemy's model. You'd see there's another epicycle we didn't notice.

Parameters X to Y encode this epicycle; parameters whatever encode the next epicycle. If you were just trying to figure out why the solar system is the way it is from observational data, you could just keep adding epicycles upon epicycles, but it really took one mind to integrate it all in and say, “Here's what makes more sense overall.” This is to my point that we don't really understand what to do with the models. We don't have the verbs yet.

Michael Nielsen

It is certainly interesting to think about the question where you start to apply constraints to the models, essentially saying, “What's the simplest possible explanation?” Or, “Can you give me the 90/10 explanation?” And go further and further in boiling it down. It might be that indeed they start out by providing a very, very complicated, many-parameter model. But you can just force the case, and that's scaffolding, which maybe is the very early days of their attempt to understand something. They're forced through that to a much simpler understanding.

Dwarkesh Patel

Sorry for misunderstanding, but it sounds like you're saying maybe there's some regularizer or some distillation you could do of a very complicated model that gets you to a truer, more parsimonious theory. Take Ptolemy versus Copernicus. You start off with lots of Ptolemy epicycles, and then you try to distill this model, and maybe it gets rid of some of the epicycles that are less and less necessary to get the mean squared error of the orbits to match.

But at some point it has to do this thing, which is to switch two things. Locally, it actually doesn't make things more accurate. It's in a global sense that it's a more progressive theory. There's some process which obviously humanity did over its span, which did that regularization or did that swap. But with raw gradient descent, I don't really feel like it would do that.

Michael Nielsen

Think about the example of going from Newtonian gravity to Einstein's general theory of relativity. These are shockingly different theories, and the question is what causes that flip. As nearly as I understand the history, what goes on is Einstein develops special relativity and pretty much straight away he understands. It's a very obvious observation. In special relativity, influences can't propagate faster than the speed of light, and in Newtonian gravity, action is at a distance.

Straight away in special relativity, you could use Newtonian gravity to do faster-than-light signaling. You could send information backwards in time. You could do all kinds of crazy stuff. It's not a big leap to realize we have a big problem here. That's the forcing function there. You've realized that your old explanation is not sufficient. You need something new.

Then you're going to start by doing the simplest possible stuff. It just turns out that a lot of that stuff doesn't work very well, so you're forced to go through these steps where gradually it gets more complicated, and it's wrong in a variety of ways. The final theory appears shockingly simple and beautiful, but it's gone through some somewhat ugly intermediate stages.

Dwarkesh Patel

If you're thinking about what it looks like to have AI accelerate science, there's one path for well-understood domains where we just want local solutions, like how a protein folds. We just train a raw model using gradient descent. Then there's things like coming up with general relativity, where you couldn't really just train on every single observation in the universe and hope that general relativity pops out. What would it require? It also certainly wasn't immediately discovered.

Michael Nielsen

It was decades of thought. You'd need independent research programs where people start off with these biases, where Einstein is initially motivated by this thought experiment of whether you can distinguish the effect of gravity from just being accelerated upwards. You just need different AI thinkers to start off with these initial biases and see what can germinate out of them. The verification loop for that might be quite long, but you just need to keep all those research programs alive at the same time.

Dwarkesh Patel

This point you make about keeping all the different research programs alive, I think that is very important and central. A great example is situations where the same answer has been correct in some circumstances and wrong in other circumstances.

The planet Uranus was not in quite the right spot, and people famously predicted the existence of Neptune on this basis. Wonderful, massive success for Newtonian gravity. The planet Mercury is not in quite the right spot. You predict the existence of some other distorting planet. It turns out that doesn't exist.

Actually, the reason Mercury is not in the right spot is because you need general relativity. You've pursued very similar ideas, and it's been very successful in one case, and it's been completely and utterly unsuccessful in the other case. A priori, you can't tell which of these is the thing to do, and you actually need to do both.

Michael Nielsen

This is certainly very true in the history of science. This kind of diversity, where you just have lots of people go off and pursue lots of potentially promising ideas, you just need to support that for a long time. It's hard to do that for a variety of reasons, but it does seem to be very, very important.

Dwarkesh Patel

This example of Uranus versus Mercury is very interesting. I think it illustrates the difficulty with falsificationism. The orbit of Uranus is in some sense falsifying Newtonian mechanics. But then you make some ancillary prediction that says, “Oh, the reason this is happening is there must be another planet which is perturbing Uranus's orbit.”

I think it's Le Verrier in 1846. “Point a telescope in the right direction, you find Neptune.” But with Mercury, it's observed that the ellipse which forms its orbit is rotating 43 arcseconds more every century than Newtonian mechanics would imply, so people say that there must be a planet inside Mercury's orbit. They call it Vulcan and point the telescopes. It's not there.

But if you're a proper Newtonian, what you do is say, “Well, maybe there's some cosmic dust that's occluding this planet, or maybe the planet is so small we can't see it, or let's build an even more powerful telescope, or maybe there's some magnetic field which is occluding our measurement.”

Michael Nielsen

And this happens over and over. There are just so many stories which are exactly like this. An example I love from the 1990s: some people noticed that the Pioneer spacecraft weren't quite where they were supposed to be. You can get very excited about this: “Oh my goodness, general relativity is wrong. Maybe we're going to discover the next theory of gravity.”

Today, the accepted explanation is that there's just a slight asymmetry in the spacecraft. It turns out that the thermal radiation is slightly larger in one direction than the other, and that's causing a tiny little acceleration towards the Sun. Most of the time when there are these apparent exceptions, it's just something like that going on. It's very much like the Mercury–Vulcan case.

But every once in a while, it's not. A priori, you can't distinguish these. Science is just full of these.

Dwarkesh Patel

It's funny, too, the way we tell the history of science. It sounds so simple. You just focus on the right exception, and you realize that you need to throw out the old theory, and lo and behold, your Nobel Prize awaits. But in fact, these exceptions are all over the place. 99.9% of the time, it just turns out to be some effect like this thermal acceleration in the case of the Pioneer spacecraft. Unfortunately, there's a lot of selection bias going into those stories.

The thing is, there's no ex ante heuristic which tells you which case you're in. To spell out why I think this is important, some people have this idea that AI is going to make disproportionate progress towards science because it makes disproportionate progress towards domains where there's tight verification loops. It's really good at coding because you can run unit tests.

Science may be similar because you can run experiments. What that doesn't appreciate is that there's an infinite number of theories that are compatible with any given experiment. Over time, why we latch onto the one we think is more correct in retrospect is, as we're discussing, hard to articulate.

Lakatos has all kinds of interesting examples in the book about these hostile verification loops that are extremely long-lasting. One he talks about is Prout. There's this chemist in 1815 who hypothesizes that all atomic nuclei must have whole-number weights. They're basically all made of hydrogen.

The reason he thinks this is because if you look at the measured weights of all elements, it does seem that almost all of them have whole-number weights. But then there are some exceptions. For example, chlorine comes out at 35.5. So then there are all these ad hoc theories that people in this school keep coming up with, like, “Maybe there's chemical impurities.” But there's no chemical reaction you can do which seems to get rid of this.

Maybe it's fractions of whole numbers, so 35.5 can be halves. But actually, if you measure chlorine even closer, it's 35.46, so it's getting further away from the correct fraction. Later on, what is discovered is that what you're actually measuring is different isotopes, which cannot be chemically distinguished. They can only be physically distinguished.

So you have 85 years before we realize what an isotope is, where the verification loop is actively hostile against the correct theory. There's no ex ante reason it's the preferred theory. As a community, we should just have people try to integrate new observations, even if they don't seem to fit their school of thought, and hopefully enough of that happens.

Anyways, I guess the thing I'm trying to articulate is the difficulty with automating science. The question is, where is the bottleneck at some level? Are we primarily bottlenecked on one type of thing, or are we bottlenecked on multiple types of things?

Certainly, talking to structural biology people, they seem to think that AlphaFold was an enormous advance. It was a shock. At some level, yes, AI can certainly help us speed up science. It is helping with a certain type of bottleneck. That doesn't mean, though, as you're saying, that it's necessarily going to help with all kinds of bottlenecks.

I suppose the question you're pointing at is, what are the types of bottlenecks that remain, and what are the prospects for getting past them?

Michael Nielsen

Even in the case of coding, it's really interesting talking to programmer friends. At the moment, they're all in this state of shock and high excitement, and they're all over the place. You do wonder where the bottleneck is going to move to. Certainly, one thing that a lot of them seem to be bottlenecked on now is having interesting ideas, and in particular, having interesting design ideas.

There's not really a verification loop for knowing that a design idea is very interesting. They're no longer nearly as bottlenecked by their ability to produce code, but they are still bottlenecked by this other thing. Formerly, they weren't bottlenecked on it because just writing code took so much of their time.

They could have lots of ideas while they were taking 3 weeks to implement their prototype, and then they would implement the next version. Now they're taking 3 hours to implement the prototype, and they don't have as good ideas after that, from a design point of view.

4. Why aliens will have a different tech stack than us

Dwarkesh Patel

You have a very interesting take. I think it was a footnote in one of your essays, and I couldn't find it again, which was that it's very possible that if we met aliens, they would have a totally different technological stack than us. That contradicts a common assumption I had that I never questioned, which is that science is this thing you do relatively early on in the history of civilization. You get to a point and have a couple hundred years of just cranking through the basics, understanding how the universe works, and you've got it. You've got science.

Then everybody would converge on the same “science.” I found that a very interesting idea, and I want you to say more about it.

Michael Nielsen

The idea there that I'm at least somewhat attached to is that the tech tree, or the science and tech tree, is probably much larger than we realize. We're in this funny situation. People will sometimes talk about a theory of everything as a potential goal for physics, and then there's this presumption that physics is done once you get there. Of course, this is not true at all.

If you think about computer science, computer science started in the 1930s, when Turing and Church and so on laid down what the theory of everything was. They just said, “Here's how computation works.” We've spent 90-odd years since then exploring the consequences of that and gradually building up more and more interesting ideas.

Those ideas, to some extent, you can regard as technology. But insofar as they're discovered principles inside that theory of computation, I think they're best regarded as science and, in some cases, very fundamental science. Ideas like public-key cryptography are incredibly deep, very non-obvious ideas which lay hidden already in the 1930s.

My expectation is that there will be different ways of exploring this tech tree, and we're still relatively low down. We're still at the point where we're just understanding these basic, fundamental theories, and we haven't yet explored them. A thing which I think is quite fun is if you look at the phases of matter.

When I was in school, we'd get taught that there are 3 phases of matter, or sometimes 4 or 5, depending on what you included. As an adult, as a physicist, you start to realize we've been adding to this list. We've got superconductors and superfluids, and maybe different types of superconductors, and Bose-Einstein condensates, the quantum Hall systems, fractional quantum Hall systems, and so on.

It's starting to turn out there's a lot of phases of matter to discover, and we're going to discover a lot more of them. In fact, we're going to be able to start to design them in some sense. We'll still be subject to the laws of physics, but there is this tremendous freedom in there.

This looks to me like we're down at the bottom of the tech tree. We've barely gotten started there, and I expect that to be the case broadly. Certainly, programming is a very natural place to look. The idea that we've discovered all the deep ideas in programming just seems obviously ludicrous. We keep discovering what seem like deep, new, fundamental ideas.

We're very limited. We're basically slightly jumped-up chimpanzees, so we're slow and it's taking us time. But what do we look like another million years in the future, in terms of all the different ideas people have had around how to manipulate computers and information? I think we're likely to discover that there are a lot of very deep ideas still to be discovered.

I think it was Knuth in the preface to The Art of Computer Programming who says something like it. He started this book back in the 1960s. He talked to a mathematician who was a bit contemptuous and said, “Look, computer science isn't really a thing yet. Come back to me when there's a thousand deep theorems.” Knuth remarks, writing the preface decades later, “There clearly are a thousand deep theorems now.”

It's really interesting to think what the long-term future is as you get higher and higher up in the tech tree, choices about which direction we go and how we choose to explore. It's potentially the case that different civilizations or different choices mean we end up in different parts of that tree.

In particular, there are just very basic things about how we're very visual creatures, while certain other animals are much more aurally based. Does that bias the types of thoughts that you have? Then you extend it to much more exotic kinds of civilizations where maybe their biases in terms of how they perceive and manipulate the world are quite different from ours. That might make some significant changes in terms of how they do that exploration of the tech tree. It's all speculation, obviously.

Dwarkesh Patel

This is such an interesting take. I want to better understand it. One way to understand it is that there might be some things which are so fundamental and have such a wide collision area against reality that they're inevitably going to discover, like general relativity.

Michael Nielsen

Numbers. Numbers. Of all the intelligences in the Milky Way galaxy—maybe that number is 1. Well, actually, arguably we've already increased the number. But of all of those, what fraction have the concept of counting? It does seem very natural.

What fraction have discovered the idea of some kind of decimal place system? Interesting question. Maybe we're missing something really simple and obvious that's actually way better than that. What fraction got there immediately? What fraction had to go through some other intermediate state? What fraction uses linear representations versus a 2-dimensional or a 3-dimensional representation? I think the answers to these questions are just not at all obvious. It's a lot of design freedom.

Dwarkesh Patel

On theoretical computer science, this is going to be extremely naive and arrogant, but I took Scott Aaronson's class on complexity theory, and I was by far the worst student he's ever had. What I remember is there was this period in which you were one of the pioneers, where we figured out the class of problems that quantum computers can solve and how it relates to problems that classical computers can solve. It was groundbreaking. It's crazy that this works.

Since then, there's literally this website called Complexity Zoo, which lists out all the complexity classes. If you have this complexity class with this kind of oracle, it's equivalent to this other class. It feels like we're building out that taxonomy.

There are a couple ways to understand what you're saying. One, maybe you disagree with me that this is actually what's happened with this field. Another is that while that might happen to any one field, who would've thought in 1880 that computer science, other than Babbage, was going to be a thing in the first place? We're underestimating how many more fields there could be. Or maybe you think both, or maybe a third secret thing. I'd be curious.

Michael Nielsen

A very common argument here is the low-hanging fruit argument. The argument that says there should be diminishing returns. In fact, empirically we see this. The number of scientists in the world has increased exponentially.

I think it's worth thinking about why you expect diminishing returns and how well that argument actually applies in practice. An analogy I like is thinking about going to an event, like a wedding, and you go to the dessert buffet. They've put out 30 desserts. Naturally, what people do is, the best desserts go first.

We don't quite have a well-ordered preference there, so maybe there's some difference, but human beings are fairly similar, so the best desserts will go first. This is an argument for why you expect diminishing returns in a lot of different fields. If it's relatively easy to see what's available and people have similar preferences, then the best stuff goes first and it just gets worse and worse after that.

If you look at a very static snapshot in time of scientific progress, maybe there's some truth to that. But if somebody is standing behind the dessert table and is replenishing and restocking the desserts and keeps adding new ones in, it may turn out that a little bit later, much better desserts appear, and you're going to go and eat those instead.

Scientific progress has a little bit of that flavor. We go through these funny time periods.

Computer science is a great example. It basically arose as a side effect of some pretty abstruse questions in the philosophy of mathematics and logic. You've got these people trying to attack these rather esoteric questions that seem quite high up in exploration, and they discover this fundamental new field. All of a sudden, there's an explosion there.

The diminishing returns argument just didn't apply there. We just weren't able to see what was there. This has been the case over and over again. New fields arrive and, boom, it's easy to make progress again. Young people flood in because you can be 21 and make major breakthroughs rather than having to spend 25 years mastering everything that's been done before. It's obviously very attractive.

I'm not sure anybody understands very well the dynamics of that, or how to think about why the structure of knowledge is that way—where these new fields keep opening up. But it does seem empirically to be the case.

Dwarkesh Patel

Despite the fact that this is the case, take deep learning. Obviously, this is an example of a new field where 21-year-olds can make progress, and it's relatively new—15 years or so since it got back into high gear. But already we're in a stage where you need billions, tens of billions, or hundreds of billions of dollars to keep making progress at the frontier.

Michael Nielsen

There are a couple of ways to understand that. One is that it actually is harder than the kinds of things the ancients had to do, or is more intensive, at least. Second, it might not have been, but because our civilizational resources are so large—the number of people is so large, the amount of money is so large—we can basically make the kind of progress it would have taken the ancients forever to make almost immediately. We notice something is productive and immediately dump in all the resources.

Dwarkesh Patel

But it's also weird that there aren't that many of them. I feel like deep learning is notable because it is one big exception to the fact that it's hard to think of other examples.

Michael Nielsen

I think that's a consequence of the architecture of attention.

Dwarkesh Patel

At any given time, there's always a most successful thing. If deep learning wasn't a thing, maybe you'd be talking about CRISPR. Maybe we wouldn't think about solving the protein structure prediction problem as a success of AI. Maybe we would have figured out how to do it with curve fitting, more broadly construed, and we'd just be like, “Wow, that took a lot of computing resources.” But protein structure prediction might be an enormously important thing. There is always our biggest thing.

Michael Nielsen

What you're pointing at is more a consequence of the way in which attention gets centralized.

Dwarkesh Patel

It's basically fashion, is what I'm saying.

Michael Nielsen

It's not just fashion, but there is some dynamic there. There's a very interesting and important implication of this idea: that the branching is so wide, so contingent, and so path-dependent that different civilizations would stumble on entirely different technology stacks. There's a very interesting implication that there will be gains from trade into the far, far future, which might actually be one of the most important facts about the far future in terms of how civilizations are set up, how they coordinate, and how they interface.

There's not this “go forth and exploit.” There are humongous gains from trade between adjacent colonies or whatever.

Dwarkesh Patel

Sort of. There's a question of what's actually hard. If it's just the ideas, well, those spread relatively quickly. It's relatively easy to share ideas. If it's something more, it's almost a Dan Wang kind of idea, where there's some notion of capacity. You need all the right techs, you need all the right manufacturing capacity, and so on.

So civilization A has a very different kind of manufacturing capacity, and it's just not so easy to build in civilization B. Even if civilization B is ahead, I think that becomes true. There is a comparative advantage which is going to provide massive benefits to trade in both directions. Eventually, you expect some diffusion of innovation.

It is funny to think about what the barriers are there. A fun thought experiment I like to think about is GitHub but for aliens. Somebody presents you with all of the code from some alien civilization. I don't even know what code means there, but their specification of algorithms would have many interesting new ideas in there, and it would take forever for human beings to dig through and try and extract all of those.

The origin of this for me was thinking about proteins in nature. We've been gifted this incredible variety of machines which we don't really understand at all. We just have to go and try and understand them on a one-by-one basis. We're still understanding hemoglobin and insulin and things like this. There are hundreds of millions of proteins known.

So it is a little bit like that. We've been gifted by biology this immense library of machines, no doubt containing an enormous number of very interesting ideas, and we're just at the very, very beginning of understanding it.

Michael Nielsen

I suppose your point—I need to relabel your argument slightly—is that you think of that as a gift from an alien civilization, which obviously it isn't, but you think of it that way. And, oh my goodness, there's so much in there and we're going to study it. Goodness knows how long we could continue to study it. There are tens of thousands of papers about hemoglobin and things like that, and we still don't understand them, and yet we're getting so much out of it. Just think about insulin alone. It's such an important thing.

Dwarkesh Patel

That's an incredibly useful intuition pump that you have on Earth. I had Nick Lane on, where he had this theory about how life emerged, but whatever theory you have, something like DNA has had 4 billion years. You have an alien civilization come here and be like, “There's all these interesting things to learn about materials science.”

Think about kinesin walking along. We know almost nothing about these proteins, and yet the tiny few facts we do know are just incredible. The ribosome is another example, this miraculous sort of device, a little factory. It's all seeded by this particular chemistry on Earth, with nucleic acids and carbon-based life forms.

That chemistry gives rise to all of these interesting things which an alien civilization would find very interesting. That very seed, which must be one among trillions of possible seeds of general intellectual ideas, leads to all this fecundity. That's a very interesting intuition pump.

I want to meditate on this “gains from trade” thing because I feel like there's something very interesting about this idea: if you have this vision of how technology progresses and how it may be different in different civilizations, it actually has important implications about how different civilizations might interact with each other. The fact that there are going to be these huge gains from trade makes friendliness much more rewarding?

Michael Nielsen

Yes. That's a very important observation. I hadn't thought about that at all. That is a very interesting observation.

It's funny. Comparative advantage is something that people love to invoke, and it's a very beautiful idea, obviously. There are limits to it. Chimpanzees can do interesting things, but we don't trade with them. I think it's interesting to think about the reasons why.

Part of it is just power. Once there's a sufficiently large power imbalance, very often—not always, but very often—groups of people seem to shift into this other mode where they just seek to dominate. Maybe there's something special about human beings, but maybe it's also a more general thing. You need all these special things to be true before groups will trade. It's not necessarily obvious.

I think the big things going on here are, one, transaction costs. Two, comparative advantage does not tell you that the terms on which the trade happens are above subsistence for any given producer. People often bring this up in the context of, “Well, humans will be employed even in a post-AGI world because of comparative advantage.”

There are 5 different ways that argument breaks down, but the easiest way to understand it is: Why don't we have horses all around on the roads? Because there's some comparative advantage between cars and horses. One, there are huge transaction costs to building roads that are compatible with horses and cars at the same time.

In a similar way, AI systems thinking at 1,000 times the speed that can shoot their latent states at each other are going to find it way more costly than the benefit of interacting with a human being in the supply chain.

Second, just because horses have a comparative advantage mathematically does not mean that it is worth paying $100,000 a year, or whatever it costs, to sustain a horse in San Francisco. That subsistence isn't going to be worth the benefit you get out of the horse. I do think it's interesting, the sheer fact. My expectation and my intuition obviously differ a great deal from yours on this.

Most parts of the tech tree are never going to be explored. There are just too many interesting ways of combining things. There are too many deep ideas waiting to be discovered, and not only we, but nobody ever, is going to discover most of them. So choices about how to do the exploration actually matter quite a bit. It's something I really dislike about technological determinist arguments.

I'm willing to buy it low enough down, when progress is relatively simple. But higher up, you start to get to shape the way in which you do the exploration. And it's interesting: we are starting to shape it in interesting ways. There are various technologies that have been essentially banned. You think about DDT, chlorofluorocarbons, restrictions on the use of nuclear weapons, and the Nuclear Non-Proliferation Treaty.

Those kinds of things weren't done before the fact, but they're starting to get pretty close in some cases, where we just preemptively decide, "Oh, we're not going to go down that path." So that starts to look like a set of institutions where we are actually influencing how we explore the tech tree.

On where you would see these gains from trade, obviously you'd see the most where it's pure information that could be sent back and forth, because information has this quality where it is expensive to produce, but cheap to verify and cheap to send. It'll be interesting how much of future productivity can be distilled down to information.

Right now, it's hard to do. If China's really good at manufacturing something, there's this process knowledge that's in the heads of 100 million people involved in the manufacturing sector in China. But in the future, it might be easier if AIs are doing it. The question is to what extent our fabrication gets very uniform and gets really commoditized.

3D printers have been the next big thing for at least 20 years now. Why do they still not work all that well? Why are they still not at the center of manufacturing, and what comes after that? It is funny to look at the ribosome by contrast, which really is at the center of biology in a whole lot of really interesting ways.

Whether or not that's the future of manufacturing is something very simple, where everything goes as throughput through a bioreactor or something like that. You send the information, and then you grow stuff, or you have some 3D printer that actually works. If they're good enough, then it does become much more a pure information problem, and some of this process knowledge becomes much less important.

5. Are there infinitely many deep scientific principles left to discover?

Dwarkesh Patel

Can I ask a very clumsily phrased question? There are a couple of these deep principles that we've discovered. One is this idea that if there's a symmetry across a dimension, it corresponds to a conserved quantity. It's a very deep idea. There's another—which you've written a lot about, written a textbook about, in fact—about ways to understand what kinds of things you can compute, what kinds of physical systems you can understand with other physical systems, what a universal computer looks like, et cetera.

Is your view that if you go down to this level of ideas, like Noether's theorem or the Church–Turing thesis, that there's an infinite number of extremely deep such principles? Because I feel what makes them special is that they themselves encompass so many different possible ways the world could be. But, no, the world has to be compatible with a couple of these very deep principles.

Michael Nielsen

I don't know. All I have here is speculation and instinct. My instinct is that we keep finding very fundamental new things. It was quite formative for me to understand, as I gave the example before, these wonderful ideas of Church and Turing and these other people about universal programmable devices.

Then you understand later, this also contains within it the ideas of public-key cryptography. Then you understand later that this also contains within it the ideas people refer to as cryptocurrency. There's a very deep set of ideas there about the ability to collectively maintain an agreed-upon ledger, which is built upon this.

It's taken many years to figure out the right canonical form of those. Just this fact that you keep finding what seem like deep new fundamental primitives has been a very important intuition pump for me. I've given that particular example, but I think you see that same pattern in a lot of different areas.

Dwarkesh Patel

What is your interpretation, then, of this empirical phenomenon where whatever input you consider into the scientific process or technological progress, economists have studied this a million ways? It just seems to require a very consistent rate of X percent more researchers per year.

There's this famous paper from a couple of years ago by Nicholas Bloom and others where they say, "How many people are working in the semiconductor industry, and how has it increased over time through the history of Moore's law?" I think they find that Moore's law means transistor density increases 40% a year, but to keep that going, the number of scientists has increased 9% a year in the semiconductor industry. They go through industry after industry with this observation.

Is your view that there are these deep ideas, but they keep getting harder to find? Or is there another way to think about what's happening with these empirical observations?

Michael Nielsen

First of all, all of their examples are narrow. They pick a particular thing, and then they look at a particular metric. GPUs don't show up there. All of a sudden, you get this ability to parallelize, and that's really interesting. There are a lot of external consequences.

Basically, they have these simple quantitative measures. They look at it in agricultural productivity. They look at it in a whole lot of different ways, but you do have to focus narrowly. I'm certainly interested in the fact that new types of progress keep becoming possible.

But I think even there, there does still seem to be some phenomenon of diminishing returns. Is that intrinsic? Is that something about the structure of the world? What is it? One thing which hasn't changed that much is the individual minds which are doing this kind of work.

Maybe those should be improved as well, or some feedback process going on there. Maybe that changes the nature of things. I look at scientific progress up until, let's say, 1700, and it was very slow, and also very irregular.

You had the Ionians back five centuries before Christ doing these quite remarkable things, and so much knowledge would get lost, and then it would be rediscovered, and then it would be lost again. You'd have to say that progress was very slow. It's partially just bound up with the fact that there were some very good ideas that we just didn't have.

Even once you've had the ideas, you need to build institutions around them. You actually need to solve a whole lot of different problems about training, allocation of capital, and all these kinds of things. Even just basic security for researchers, so they're not worried about the Inquisition or things like that. There are all these complicated problems.

You solve all those complicated problems, and then all of a sudden, boom, there's a massive burst of scientific progress. If there's some kind of stagnation, if you're not changing those external circumstances, yes, you may start to get diminishing returns again. But that doesn't mean there's anything intrinsic about the situation. Maybe something external needs to change again.

Obviously, a lot of people think AI is potentially going to be a driver. It certainly will at some level. To that extent, you can think of a lot of modern scientific instrumentation as really, at some level, robots. What is the James Webb Space Telescope? It's unconventional, maybe, to describe it as a robot, but it's not completely unreasonable either.

It is an example of a highly automated, very sophisticated system with electronically mediated sensors and actuators, where machine learning is being used to process the data. In that sense, we're already starting to see that transition. We've been seeing it for decades.

Dwarkesh Patel

I have this “smoke a joint and take a puff” thought, which—I think we've had a few. I think we're getting to that part of the conversation, and then you can help me get my foot out of my mouth and figure out a more concrete way to think about it.

To your point that there was the Industrial Revolution, the Enlightenment, and now there's AI, and each might be a different pace or a different way in which science happens. If you think about the pace of how fast such transitions have been happening, you can draw over the long span of human history this hyperbolic rate of growth that is increasing over time as well.

A hundred thousand years ago, you had the Stone Age. You go back even much further—how long have primates been around? It would be millions of years. A hundred thousand years ago, the Stone Age, then 10,000 years ago, the Agricultural Revolution, then 300 years ago, the Industrial Revolution, each marked by this increase in the rate of exponential growth.

Then people think it's going to happen again with AI. But that would happen potentially even faster. It would not have occurred to somebody at the beginning of the Industrial Revolution that the next demarcation in this trend will be artificial intelligence. So, if things are getting faster and it's hard to anticipate what the next transition will be, I guess we just think of this singularity between now and AI as what distinguishes the past from the future.

But applying the same heuristic that many people in the past should have had, maybe the “Intelligence Age” is also quite short, and the next thing after that, we don't even have the ontology to describe what it is. The future will not think of the past as pre-intelligent AI and post-AI.

Michael Nielsen

No, obviously we can't prove this, but it certainly seems quite plausible. Part of the issue is just that the substrate we have available to conceive seems all wrong. You can't speculate with a bunch of chimpanzees about what it would be to have language. Just to pick a major transition in the past, the transition itself is the thing. It seems likely.

If we're talking about “taking a puff” kind of thoughts, I'm certainly amused by the idea that there's going to be some transition involving artificial general intelligence using classical computers. But actually, there'll be an interesting transition with quantum computers as well. They're probably capable of a strictly larger class of potentially interesting computations.

So maybe the character of AQGI, or whatever it should be called, is actually qualitatively different. So maybe there's a brief period between those 2 things. As I say, this is just speculation, but it's certainly amusing.

Dwarkesh Patel

Is there a reason to think that? From what I understand, for decades people like you have put pretty tight bounds on the kinds of things quantum computers are going to do. It'll speed up search somewhat. The kinds of things it speeds up extremely, like Shor's algorithm, seem like—again, maybe this is to your point that we can't predict in advance what's down the tech tree—but at least from here, it seems like you break encryption, but what else are you using Shor's algorithm to do?

Michael Nielsen

We've only been thinking about it for 40 or so years—not for very long—and we haven't thought that hard about it as a civilization. Does it turn out that it's very narrow? Maybe. Does it turn out that it's very broad? That's also a really radical expansion that seems distinctly possible.

Keep in mind as well, we've been doing it without the benefit of having the devices. That's a pretty big bottleneck to have. If you're thinking about computer science in the 1970s and you're like, “It can do AND/OR, what can come out of that?” you can't anticipate Bitcoin. You can't anticipate deep learning. Maybe you could if you were sufficiently bright, but it is a pretty hard situation.

6. What drew Michael to quantum computing so early?

Dwarkesh Patel

What is your inside view, having been in and contributing to quantum information and quantum computing back in the 1990s and 2000s? What is your telling of the history of what was the bottleneck? What was the key transition that made it a real field? How do you rank the contributions from Feynman to Deutsch to everybody else who came along?

Michael Nielsen

Let's just focus on the question about what actually changed. Why was quantum computing not a thing in the 1950s? It could have been. Somebody like John von Neumann is a good example. He was absolutely pioneering computation. He also wrote a very important book about quantum mechanics and was deeply interested in it. He could have invented quantum computing at that time, and I think there were quite a number of people who potentially could have.

So why do we have these papers by people like Feynman and Deutsch in the 1980s? Those are generally regarded as the foundation of the field. There are some partial anticipations a little bit earlier, but they were nowhere near as comprehensive and nowhere near as deep. You should ask David. You can't ask Feynman, unfortunately, but he'll know much better than I do.

A couple of things that I think are interesting. One is that computation became far more salient in the late 1970s and early 1980s. It just became a thing which many more people were interested in, partially for very banal reasons. You could go and buy a PC. You could buy an Apple II. You could buy a Commodore 64. You could buy all these kinds of things. It became apparent to people that these were very powerful devices, very interesting to think about.

At the same time, in the quantum case, that was also the time of the Paul trap and the ability to trap single ions. Up to that point, we hadn't really had the ability to manipulate single quantum states. You got these 2 separate things that, for historically contingent reasons, had both matured around 1980 or so. Somebody like von Neumann could have had the idea earlier, but it is quite an interesting factor.

There's a story about Richard Feynman. He went and got one of the first PCs around 1980 or 1981. He was apparently so excited with this device that he actually tripped and hurt himself quite badly carrying his brand-new computing device. That's a very historically contingent coincidence, having somebody who's very talented and understanding of quantum mechanics also just very excited about these new machines.

It's not so surprising, perhaps, that he's thinking about it then. What similar story could you have told 10 years earlier? The conditions don't exist for it. It's quite a banal story, but—

Dwarkesh Patel

One of the things we were going to discuss was this idea you had about the market for follow-ups. I think this is the perfect story to discuss it because you wrote the textbook about the field. Quantum Computation and Quantum Information, “Mike and Ike,” is the definitive textbook on quantum information. You presumably came in after Deutsch, but you, in the 1990s, somehow identified it as the thing that is worth following up on and building on.

Instead of talking about it more abstractly, I'd love to just hear the firsthand story of how you knew that this is the thing to do. Of all the things that were happening in physics and computing, how did you decide you wanted to think about this problem?

Michael Nielsen

Richard Feynman writes this great paper in 1982. David Deutsch writes an absolutely fantastic paper in 1985, sketching out a lot of the fundamental ideas of quantum computing. I'm 11 in 1985. I'm not thinking about this. I'm playing soccer and doing whatever.

But in 1992, I took a class on quantum mechanics that was really terrific, given by Gerard Milburn. I just went and asked Gerard one day after the fifth lecture or something. I said, “Do you have any papers or whatever that you could give me?”

He said, “Come by my office in a couple of days' time.” I did, and he presented me with a giant stack of papers, which included the Deutsch paper, the Feynman paper, and a whole bunch of other very fundamental papers about quantum computing and quantum information at a time when essentially nobody in the world was working on it.

He was. I think he wrote the very first paper that proposed a practical approach to quantum computing. It wasn't very practical, but it was actually in a real system. In some sense, I'm benefiting from the taste of this other person.

As soon as I read the papers—these are exciting papers. They're asking very fundamental questions, and you realize, I can make progress here. These are things that one could potentially work on. Deutsch has this conjecture, or thesis, or whatever you'd call it, that a universal model—a quantum Turing machine—should be capable of efficiently simulating any physical system at all.

This is a very provocative idea. I think in that paper, he more or less claims that he's proved it. I'm not sure everybody would agree with that. There are questions about whether or not you can simulate quantum field theory effectively. That kind of question is very interesting and very exciting.

It's obviously a fundamental question about the universe. He has some wonderful ideas in there about quantum algorithms, where they come from, what they mean, and what they relate to the meaning of the wave function. Questions like this are still not agreed upon amongst physicists. There's just some sense of, “Oh, I am in contact with something which is (A) deeply important, and (B) we as a civilization don't have this.” Of course, you start to focus your attention a little bit there.

I'm not sure I got the answer to the question. Maybe I misunderstood the question. Maybe I'll explain the motivation first.

Dwarkesh Patel

In a previous conversation, we were discussing how you could have known in the 1940s that the Shannon theorems and Shannon's way of thinking about a communication channel is a deep idea that goes beyond the problems with pulse-code modulation that Bell Labs was trying to solve at the time, and that it applies to everything from quantum mechanics to genetics to computer science.

One of the ideas you stated that we didn't get a chance to talk about yet was that Shannon published this paper. There are all these other papers, but there's some market of follow-ups where people gravitate to and build upon Shannon's work. How do they realize that that's the thing to do, and how does that process happen?

Michael Nielsen

I guess you gave your local answer. You read these papers, and you immediately realized there's work to be done here. There's low-hanging fruit. There's some deep, provocative idea that I need to better understand, and I could tractably make progress on.

To some extent, you're saying, “Okay, I wanted to get into this game of contributing to humanity's understanding of the universe,” and you are applying this low-hanging-fruit algorithm. You're like, “Relative to my particular set of interests and abilities, where should I pick up my shovel and start digging?” There it was like, “Oh, this looks like quite a good place to start digging.”

Different people, of course, chose very differently. It was a very unusual choice at the time. This was 1992. Very few people were thinking about that.

7. Does science need a new way to assign credit?

Dwarkesh Patel

Fast-forwarding a bit, I don't know how you think about your work on the open science movement now, but did it work? What does success there look like? What is the movement trying to accomplish?

Michael Nielsen

It's interesting. You didn't stop and define open science there, which 20 years ago you would have had to do. People recognize the phrase. People have some set of associations with it. Most often, they have a relatively simple set of associations. It means maybe something about making scientific papers open access. Very often, they also have some set of notions about making code openly available or making data openly available.

Those are already very large successes of the open science movement: making those salient issues. Those are issues on which people have opinions, and there are relatively common arguments. This is like the meme version: publicly funded science should be open science. That's a distillation of a set of ideas which you might be able to contest.

But if you can get people actually thinking about it and engaged with that kind of argument, that's a very fundamental issue to be considering in the whole political economy of science. If you go back 3 centuries, there was a very similar argument prosecuted, which is the question: do we publicly disclose our scientific results or not?

If you look at people like Galileo and Kepler, the extent to which they publicly disclosed their work was done in a very odd way. Sometimes they did bizarre things where they published some of their results as anagrams. They'd find some discovery, write down the result in a sentence, scramble it, and publish that. Then if somebody else later made the same discovery, they would unscramble the anagram and say, “Oh, yeah, I actually did it first.” This is not an ideal foundation for a discovery system.

It took a very long time—over a century, I think—to obtain more or less the modern ideals, in which you disclose the knowledge in the form of a paper. There is an expectation of attribution, and a reputation economy gets built. “So-and-so did this work, so they deserve the credit for that,” and that's the basis for their careers. This is the underlying political economy of science.

That made a lot of sense when you have a printing press and the ability to do scientific journals. Then you transition to this modern situation, where you can start to share a lot more. You can share your code, your data, your in-progress ideas. But there's no direct credit associated with those. It's not at all obvious how much reputation should be associated with them. That's all constructed socially. Making it a live issue is a very important thing to have done. I view that as one of the main positive outcomes of work on open science.

I'll give you a really practical example to illustrate the problem. For a long time in physics, there was a preprint culture in which people would upload preprints to the preprint archive, and in biology, this didn't happen. There was no preprint culture. That's changing now, but for a long time, this was the case.

I used to amuse myself by asking physicists and biologists why this was the case. What I would hear from biologists was they would say, “Biology is so much more competitive than physics that we need to protect our priority, so we can't possibly upload to the archive. We have to just publish in journals.”

Then I would sometimes hear from physicists, “Physics is so much more competitive than biology that we need to establish our priority by uploading as rapidly as possible to the preprint archive. We can't possibly wait to do it with the journals.”

I think this emphasizes the extent to which this kind of attribution economy is just something we construct. It's something we do by agreement. Any attempt to change that economy results in a different system by which we construct knowledge. There is this very fundamental set of problems around the political economy of science.

Dwarkesh Patel

We've got this collective project, and how we mediate it depends upon the economy we have around ideas. One of the things you've emphasized as a part of this project of open science, and we talked about it earlier, is collective science, or groups of people making progress on a problem where no individual understands all the logical and explanatory levels necessary to make a leap or a connection.

Outside of mathematics, what is the best example of such a discovery?

Michael Nielsen

I'm not sure I have a well-ordering of them to give you a best. An example that I think is very interesting is the LHC, where it's just this immensely complicated object.

Years ago, I snuck into an accelerator physics conference. I didn't know anything at all about accelerator physics, but I was just curious to see what they were talking about. This particular group of people were experts on numerical methods, in particular on inverse methods.

Inside these accelerators, you have these cascades. A particle will be massively accelerated, maybe it'll be collided, and then you'll get a shower of particles which decays and decays and decays. There's just this incredible, consequential shower, which is ultimately what you see at the detector. Then you have to retroactively figure out what produced it.

There are these very complicated inverse problems that need to be solved. You've got this final data, but you need to figure out what produced it, and that's how you look for signatures of these. Many of these people were incredibly deep experts on simulation methods for following particle tracks. This was really deep and difficult stuff.

I was like, “Wow, you could spend a lifetime just learning how to do this and how to solve some of these inverse problems, and you would know very little about quantum field theory, detector physics, vacuum physics, or data processing”—all these things that are absolutely essential to understanding, say, the Higgs boson.

I don't think it's possible for one person to understand everything in depth. Lots of people broadly understand a lot of these ideas, but they don't understand everything at the depth that is actually utilized. That's why there are these papers with well over 1,000 authors. Those people can talk to one another at a high level, but they don't understand each other's specialties in all that much depth.

Things like detector physics, vacuum physics, and solving inverse problems—this stuff is incredibly different from each other. To understand it in real detail is serious work.

8. Prolificness versus depth

Dwarkesh Patel

How do you think about prolificness versus depth? Maybe Darwin's an example of somebody who's just gestating on something for many decades. There are other examples. Einstein, during the year he came up with special relativity, was just doing a bunch of different things. And Pais talks about how they were all relevant to the eventual buildup. It's something I stress about a lot. Sometimes I feel I'm too slow.

Michael Nielsen

It's funny, though, the Darwin example is really interesting. Prolific at what? God knows how many letters he wrote. It must have been an enormous number, so he was certainly very active.

There are 2 types of work that tend to be involved in any kind of creative project. There's routine stuff, and there you just want to avoid procrastination. You just want to ask, “How do I get good at this?” or “How do I outsource it?” and “How do I do it as rapidly as possible?” You just want to avoid getting into a situation where you're prolonging it.

Then there's high-variance stuff where you actually need to be willing to take a lot of time. You need to be willing to go to different places and talk to different people, where, in any given instance, most of it is just not going to be an input.

Somehow balancing those 2 things, I think a lot of people are very good at doing one or the other, but it's almost like a personality trait which one you prefer. People tend to end up doing a lot of one and not enough of the other. So I certainly try and balance those 2 things.

Einstein is such an interesting example. 1905 is just this extraordinary year. You can delete special relativity entirely, and it's an extraordinary year. You can delete special relativity, and you can delete the photoelectric effect, for which he won the Nobel Prize, and it's still an extraordinary year—plausibly a multi-Nobel-Prize-winning year. So what's he doing? Maybe the answer is just that he's smarter than the rest of us.

There's a lot of luck as well. Certainly, for myself anyway, trying to identify those things that are routine, that I should get good at, and then just trying to do them as quickly as possible—I think that's yielded a certain amount of returns. But also being willing to bet a little bit more on myself on the variance side has also been very, very helpful.

Dwarkesh Patel

That's really hard, because intrinsically you're putting yourself in situations where you don't know what the outcome is going to be. If you're very driven to be productive, and actually mostly it's not working over there, you think, “Let's reduce this.” It doesn't feel right.

When I worked in San Francisco, a practice I used to have each day was, instead of taking the 15-minute walk to work, I would take the more beautiful 30-minute walk. Partially just because it was beautiful, but partially also as just a reminder that there are real benefits to not being efficient.

But it's not an answer to your question. Really, I think all I'm saying is I struggle a lot with the question.

Michael Nielsen

I think Dean Keith Simonton has this famous equal odds rule where he says the probability that any given thing you release—any paper, book, whatever—will be extremely important for a given person through their lifetime is not that different. What really determines in what era they are the most productive is how much they're publishing. Any given thing has equal odds of being extremely important.

I think some of the most successful creatives or scientists, they're just doing a lot. Shakespeare was just publishing a lot. Of course, then there are counterexamples. Gödel published almost nothing. But broadly speaking, you need a very good reason to not do that.

Dwarkesh Patel

It's funny, I've met a lot of people over the years who are clearly brilliant, and they're just obsessed that they are going to work on the great project that makes them famous, and they never do anything. That seems connected.

Michael Nielsen

It's a type of aversiveness. I think very often they just don't want public judgment.

Something that I would love to see is an awful lot of biographies and memoirs and histories of people who achieve a lot. I wish there were a very large number of biographies of people who are fantastically talented who just missed. I've known people who won gold medals at IMOs and things like that, who then tried to become mathematicians and failed. What happened? What was the reason? I suspect in many cases that's actually more informative than anything else.

9. What it takes to actually internalize what you learn

Dwarkesh Patel

You have this essay that I was reading before this interview about how you think about what the work you're doing is. And “writer” doesn't seem like the right label. As you say, was Charles Darwin a writer? What exactly is that label? I'm a podcaster. In a way, obviously our work is very different, but I also think a lot about what this work is and how I get better at it.

In particular, how can I make sure there's some compounding between the different people I talk to on the podcast? I worry that instead of this compounding, I build up some understanding that's somewhat superficial about a topic, and then it depreciates. I move down to the next topic, and it depreciates. There are a lot of podcasters in the world who will interview way more experts than I have, and I don't think they're much the wiser or more knowledgeable as a result. So it's clearly possible to mess this up. I wonder if you have thoughts or takes or advice on how one actually learns in a deeper way from this kind of work.

Michael Nielsen

It's an incredibly complicated and rich question. It seems like the question is, how do you make it a higher-growth context? How do you make it a more demanding context? You can do that in relatively small ways that might yield compounding returns, or you can do something that is more radical. Maybe it means starting a parallel project in which you do something that is actually quite a bit different.

There is something really interesting about how being very demanding can simply change your response to something. Something that I would sometimes do with students and sometimes with myself—it was really aimed more at myself—was have them say, some week, “I'm going to try and do this work over the coming week.” Then the next week would come by and they hadn't solved the problem. If 1 million dollars had been at stake, would you have put the same effort in? And the answer is no, invariably. They've tried, but they haven't really tried. I think that's a very familiar feeling for all of us.

You could do a lot more if you had just the right demanding taskmaster standing by you and saying, “Look, you're barely operating here.”

Dwarkesh Patel

I do wonder a little bit about what's the demanding taskmaster? What can they ask you that is going to make your preparation way more intense?

For some subjects, it is very clear how I prep. I'm doing an upcoming episode on chip design with the founder of a company that does chip design, and he wrote a textbook on it. Yesterday I went over to his office, and we brainstormed 5 roofline analyses I can do. If I understand that, I have some good understanding.

The problem is with almost every other field, there's not this curriculum. When I interviewed Ilya 3–4 years ago, it was: implement the transformer, and if you implement it, you have some nugget of understanding you have clamped down. With other fields, it's just that I vaguely understand this. It's not clamped. There's no forcing function of “Do this exercise, and if you do it, you will understand.”

Michael Nielsen

Really, what you're saying is you can do a good job at podcasting without actually attaining this kind of understanding, and that's the problem from your point of view. You want to change your job description so that you are internalizing these chunks and just getting this kind of integration each time.

It seems to me that what that means is you actually want to change the structure of the work output at some level. There’s this terrible idea that lots of people have that they should be in flow all of the time. And as far as I can tell, high performers just don't believe this at all. They're in flow some of the time.

You certainly see this with athletes. When they're actually out there playing basketball or tennis, ideally they are in flow much of the time. But when they're training, they're not. They're stuck a lot of the time, or they're doing things badly.

I wonder what that looks like for you.

Dwarkesh Patel

I would be extremely satisfied with that. The problem is I just don't know what the equivalent of doing 64 laps is. This is something you can change by choosing guests where there is a legible curriculum, so maybe it's a mistake not to have done that.

Also, there's no real way to prepare for Terence Tao. There's no plausible curriculum for that. There are many failure modes, but one long-term dynamic I'm worried about is that you can have a good podcast and reach a local maximum, but for no particular guest or topic are you going deep enough.

My model of learning is that if you don't really understand the deeper mechanism, you're just mapping inputs and outputs of a black box. That just fades incredibly fast, or it's not worth it in the first place. You move on and it's over. You need to build the intermediate connection.

AI, in a weird way, is really easy for that reason, because there is a clear thing you can do. Just implement it, and then you understand it. If I applied that criterion elsewhere, do I just not do history episodes?

Michael Nielsen

Exactly. Ada Palmer was wonderful to talk to and incredibly interesting. But for you personally, what changed?

Dwarkesh Patel

There are some things I learned. If I had allocated more time, especially after the interview, to write up 2,000 words on everything I learned and how it connects to other things I know, maybe that's a thing worth doing—spreading out the episodes more and spending more time afterwards consolidating.

Michael Nielsen

I would pay infinite amounts of money if there was somebody who was really good at coming up with the curriculum, the practice problems you need to do, and the exercises you need to do after the interview to cement what you have learned.

Dwarkesh Patel

Have you tried doing that with somebody? It's hard to find someone. I haven't tried super hard, but isn't it going to be tough to find somebody who could do that for every single kind of discipline? Maybe I should just hire different ones for different topics.

Michael Nielsen

Maybe. There's something about what problem you're solving for each episode. As far as I can tell, that's the only way I really understand anything.

I get interested in something. At first, I don't even have a problem, but there's just some sense that there's some contribution to make here. Gradually, you hone in, and there's a problem. Funnily enough, spending time stuck is incredibly important. That used to just be annoying. Now it seems like it's maybe even the most important part of the whole process.

That hard-won nature of it means that I internalize it afterwards. I've written 10,000-word essays in a couple of days, and I've written them in 3 months or 6 months. I feel like I didn't learn very much from the ones that only took a couple of days. Whereas some of the ones that took 3 months, 15 years later, I'll still remember.

Dwarkesh Patel

Can you describe, outside of physics, how you learn from the ones that took 3 months?

Michael Nielsen

By far the most common thing is that there's always some creative artifact. Sometimes it's a class. Sometimes it's engagement with a group of people who are working on some collective creative artifact together. You might not even be aware of it, but you're acting as an input to their creative ends in some way. Sometimes it's an essay or a book or whatever.

It's one of the reasons why I often quite enjoy doing podcasts. I said yes to coming here partially because I know you ask unusually demanding questions. That's an attempt to get this sort of perspective from a different kind of forcing function—to pick the most demanding creative context.

For this interview, I went through 3 lectures of Susskind’s special relativity book. The problem is that there's almost no practice problems in it. So I hired a physicist friend. I haven't done it yet, but for every lecture I want a bunch of practice problems to go through, and I'm planning on being appropriately humbled.

Dwarkesh Patel

How do you make it as brutal as possible?

Michael Nielsen

The higher you can raise the stakes, the better. The interview is in some sense high stakes, but it also doesn't necessarily test deep understanding. I don't think the interview is that high stakes. You're not writing a book about special relativity, and you're not trying to write a book that replaces whatever the existing standard textbook is. That's really high stakes.

By the way, a phrase that I find particularly difficult is “going deep” on a subject. It turns out different people have different ideas of what this means. For some people, it means they read a couple of blog posts. For some people, it means they read a book. For some people, it means they wrote a book about it.

The standard you hold yourself to determines a lot about your ability to integrate knowledge in this way. I found that I'm in some sense able to move much faster on some things through the help of AI, but I don't know if I'm learning better.

I think it's probably because the hardest thing, the thing that is most demanding, is so aversive that you try to take any excuse you can to get out of it. Just having a back-and-forth conversation with an LLM where you gloss over the difficult parts—it's entertaining, but not necessarily anything else. It's such an easy way to get out of the thing.

In fact, it makes it easier because instead of doing some intermediate thinking, there's always a next question you can ask a chatbot.

Dwarkesh Patel

Yeah. And it's somewhat valuable. That's part of the seductiveness, of course. It's not actually useless. But it can substitute for actually doing the thing that maybe you should be doing.

It's interesting. To what extent should you be outsourcing that kind of stuff? It's an interesting judgment call.

Michael Nielsen

There is a whole bunch of routine work that you want done. It's low value for you, so if you can get a chatbot to do it, you may as well.

Somebody interviewed the pioneering computer scientist Alan Kay years ago, and he was asked what he thought about Linux. If I remember his answer correctly, he basically said, “It doesn't have anything to do with computer science. It's just a great big ball of mud. There are a few interesting ideas in there which are worth understanding, but mostly all you're learning is stuff about Linux. You're not actually learning anything which is transferable.”

I thought that was very interesting. There's a certain kind of seductiveness to some things where it's sort of a Rube Goldberg machine. You can just learn about all the bits, and it feels entertaining. But if you step back and think about what you're actually doing here, it might not actually be meeting your objectives.

Maybe you want to become a systems administrator, and learning Linux is a great use of your time. There's no harm in that at all. But if your objective is to understand the fundamentals of computing, it's much less clear that that's a good use of your time.

It was certainly an answer I've thought a lot about, where, for a certain type of mind, there is a seductiveness in just learning systems and confusing that with understanding.

Dwarkesh Patel

Okay, I'll keep you updated on how this goes. I owe you a text within a month about some revamped learning system.

Michael Nielsen

I'd be really curious.

Dwarkesh Patel

It's also true that tiny incremental improvements in this are just worth so much. It's the main input into the podcast. It's great that the bookshelves are fancy and I've got a blackboard or whatever, but really the thing that makes the podcast better is if I can improve the learning I do. So yes, it's worth every morsel of improvement.

All right, thanks for the therapy session. Great note to end on. Thanks, Michael.

Michael Nielsen

All right. Thanks, Dwarkesh.

Michael Nielsen:为什么外星文明会拥有与我们不同的技术栈 — 文字稿与摘要 | BidClub