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The Cognitive Revolution

Detailed conversations with AI researchers and builders about frontier models, agents, safety, policy, and the path toward advanced intelligence.

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177 EPISODESENTRACKED SHOW
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The Cognitive RevolutionEN · 121 min

Universal Medical Intelligence: OpenAI's Plan to Elevate Human Health, with Karan Singhal

Nathan LabenzKaran Singhal

OpenAI’s health strategy is scaling through ChatGPT Health, which reaches more than 230 million weekly users and is planned to connect records, wearables, and Apple Health while remaining free without rate limits and excluding health data from foundation-model training.Frontier models reached attending-physician territory in one hospitalization, yet embodied context remains a human edge; HealthBench Hard is only around 40%, while Penda Health’s randomized study shows statistically significant outcome improvements and adoption is targeted for the end of 2026.

The Cognitive RevolutionEN · 98 min

Material Progress: Developing AI's Scientific Intuition, with Orbital Materials' Jonathan & Tim

Jonathan GodwinTim Duignan

Orbital Materials is testing whether AI can turn materials discovery into a predictable engineering loop, with generative models, force prediction, and a wet lab narrowing candidates until roughly 90% of pre-synthesis questions are answered.With less than $40 million raised, it is targeting data-center thermal-management and CO2-capture materials, but regeneration economics, scale limits, and unconfirmed scientific results—including a potassium-channel mechanism—remain key milestones to monitor.