PERSON DIRECTORY
Tim Opler
Host of Biotech Hangout. Tim Opler appears in 10 indexed conversations across Biotech Hangout. This directory brings every appearance, source, TL;DR, digest, and transcript into one searchable feed.
10 EPISODES1 SHOW
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Episode 143 - May 30, 2025
Chris GarabedianJosh SchimmerNina KjellsonMike YeeTim Opler
Summit’s PD-1×VEGF bispecific missed overall survival at p=0.0575, sending shares down 25% despite a PFS hit and 20% lower mortality risk in Western patients.Tim Opler sees VEGF×PD-1 becoming oncology’s backbone, while Pfizer’s 3SBio license and Seagen acquisition give it control for ADC combinations.Macro uncertainty favors discounted commercial-stage M&A, and Gilead’s June 19 lenacapavir PDUFA will test FDA functionality.