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Dwarkesh Podcast

Deeply researched interviews.

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Dwarkesh PodcastEN · 110 min

Adam Marblestone – AI is missing something fundamental about the brain

Adam MarblestoneDwarkesh Patel

Adam Marblestone’s differentiated hypothesis is that evolution encoded many stage-specific loss functions and developmental curricula, helping explain how a 3-gigabyte genome can produce sample-efficient intelligence.The investable timeline is roughly 10 years, with a transformative event still more than five years away; meanwhile, low-billions neuroscience funding and cheaper connectomics could test the thesis against trillions in GPU capex, while reward machinery remains an alignment risk.