PERSON DIRECTORY
Dwarkesh Patel
Host of Dwarkesh Podcast. Dwarkesh Patel appears in 66 indexed conversations across Dwarkesh Podcast, Hard Fork, The a16z Show. This directory brings every appearance, source, TL;DR, digest, and transcript into one searchable feed.
Evolution designed us to die fast; we can change that — Jacob Kimmel
Jacob Kimmel argues aging was weakly optimized by evolution, making partial longevity gains tractable, while NewLimit uses sparse perturbation data and models to search roughly 10^16 transcription-factor combinations.The commercial opportunity could span everyone, but first medicines are expected to add multiple healthy years rather than deliver immortality, with durability evidence currently limited to several weeks and reimbursement distorted by three-to-four-year US insurer churn.