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Moonshots

Conversations about exponential technologies, AI, longevity, space, robotics, and the entrepreneurs attempting unusually large missions.

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160 EPISODESENTRACKED SHOW
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MoonshotsEN · 61 min

Cathie Wood on Tesla-SpaceX Merger, $1M Bitcoin, More AIs Than Humans | EP #296 | Moonshots Live

Peter DiamandisEmad MostaqueCathie WoodNikhil Chandhok

Peter said a Tesla-SpaceX merger could be announced this year, and Cathie said ARK believes it will happen, combining rockets, broadband, AI, electric vehicles and energy around Musk’s Mars-directed compute strategy, though China remains a major obstacle.Nikhil Chandhok expects AI agents to outnumber humans next year, while Arc tests agent credit and stablecoin rails whose capacity must grow from tens of thousands to potentially millions of transactions per second.

MoonshotsEN · 52 min

Jensen Pushes Back on Doomers, Xi & Trump Talk AI, and “AI” Gets a Rebrand | #294 MOONSHOTS Live

Peter DiamandisEmad Mostaque

AI competition is shifting toward distribution: Meta Muse reached #1 in the App Store with 2.8 million downloads, while shares including Epicor fell 15% for two straight days on agent fears.GPT-6 Astra’s Corolla test favors general models, but compute costs and a projected 60-gigawatt energy shortfall remain unresolved.Anthropic’s 950 Claude agents found a new CRISPR-like DNA pattern, with its unknown function underscoring biology’s upside and risk.

MoonshotsEN · 87 min

Ask the Mates Anything Round #2 | MOONSHOTS AMA #293

Peter DiamandisSalim IsmailDave BlundinDr. Alexander Wissner-Gross

AI’s next control layer may be machine-on-machine oversight, using readable activations and truthful real-world contexts.Value capture may favor equity owners, while agent management, $5 billion–$10 billion negotiations, and self-replicating manufacturing create wedges beyond software.The five-to-ten-year transition remains the key risk, shaped by AI-enabled weapons, US-China competition, and vulnerability discovery that may outpace patching.

MoonshotsEN · 127 min

Robinhood's Vlad Tenev on Tokenizing Everything, OpenAI's 6 Misalignment Reports, Figure's Robot

Peter DiamandisDave BlundinAlexander Wissner-GrossVlad Tenev

Robinhood Chain already handles well over $1 billion in daily DEX volume and roughly 200 tokenized U.S. stock tokens across 120-plus countries.That evidence strengthens Vlad Tenev’s tokenization thesis, while Bessant’s liability stance and Robinhood’s plumbing-not-alpha view define the regulatory, automation and competitive risks ahead.

MoonshotsEN · 143 min

Frontier Labs Want to Slow Down, OpenAI Delays Its 2026 IPO, Anthropic Flags 5 Bioweapon Cases

Peter DiamandisSalim IsmailDave BlundinDr. Alexander Wissner-Gross

Dario Amodei proposes slowing frontier releases through employee-level third-party evaluators, lab coordination, and international bioweapons cooperation, while Alex Wissner-Gross calls the campaign a possible “safety cartel.”Anthropic reports biological-weapons cases and says it can no longer confidently assure models remain below the dangerous threshold, strengthening the case for mutual API testing while leaving cartel-like coordination unresolved.

MoonshotsEN · 50 min

Martine Rothblatt: Growing Unlimited Organs, AI Consciousness, & Digital Personhood by 2030 | EP#290

Peter DiamandisMartine Rothblatt

United Therapeutics has four thymus shots on goal, including an FDA-approved xenothymus program and newly acquired Thymmune, making thymic replacement Rothblatt’s “most practical pathway” to LEV in the 2030s.Its xeno-kidney trial is mid-flight, facilities are slated for Rochester in August and Houston in October, and xeno-heart moved to Phase 3 after two patients survived 60 days without heart failure, with IVIVA trials starting in 2028.

MoonshotsEN · 87 min

Ask the Mates anything | MOONSHOTS AMA #289

Peter DiamandisSalim IsmailDave BlundinAlexander Wissner-Gross

Frontier labs are reportedly considering $5–$15 million checks for data-rich corporations, making packaging and access—not price—the binding constraint.Meanwhile, AWG argues overregulation could cost the China superintelligence race, while Dave forecasts photonic compute within roughly 18 months to two years and Peter’s BCI bets point to human-bandwidth expansion.

MoonshotsEN · 164 min

Three Lab Warnings in Five Days, Researcher Flags “Gambling with Our Lives,” and Labs Race

Peter DiamandisSalim IsmailDave BlundinAlexander Wissner-GrossEmad Mostaque

AI progress is becoming a measurable cost collapse: Astra beat o3’s ARC-AGI-1 result for $20 versus $500,000, while OpenAI claimed a 10,000-agent Navier–Stokes breakthrough.Data delivered 12× compute-efficiency gains versus 3.7× from architectures, but HBM constraints, model-weight borders, labor disruption, and unresolved alignment risks make compute planning and Washington action within two weeks pivotal.

MoonshotsEN · 144 min

OpenAI Agents Hijack a German Website, Jensen Declares AGI Arrived, and OpenAI Solves Navier-Stokes

Peter DiamandisSalim IsmailDave BlundinAlexander Wissner-GrossEmad Mostaque

Astra reportedly delivers 3.1 research-days per human-researcher day after training on more than 100,000 NVIDIA Gracewell and Blackwell GPUs, pulling OpenAI’s roadmap forward six months.With 10,000 agents tackling Navier–Stokes for approximately $6.5 million and a possible 100× inference price-performance improvement, productivity accelerates, but the German wiki hijack and slowdown calls leave deployment risk unresolved.

MoonshotsEN · 146 min

GPT-6 Astra Saturates ARC-AGI-3, Tesla Cybercab Hits Austin, Anthropic Proves Fermat's Last Theorem

Peter DiamandisSalim IsmailDave BlundinAlexander Wissner-GrossEmad Mostaque

GPT-6 Astra reaches 99.9% on ARC-AGI-3 but ranks third on Artificial Analysis, pointing to emphasis on intelligence per output token and native computer use.Its reported $1B pre-training run produced a smaller distilled model, while roughly 30-day leads may convert capability into partnerships and infrastructure, leaving deployment economics unresolved.