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Moonshots
Conversations about exponential technologies, AI, longevity, space, robotics, and the entrepreneurs attempting unusually large missions.
BIDCLUB DESCRIPTION
Anthropic Files $965B IPO, Trump Signs AI Executive Order, and ChatGPT Crosses 1B Users | EP #262
Peter DiamandisEmad MostaqueDave BlundinDr. Alexander Wissner-Gross
Anthropic’s confidential IPO could make frontier AI a public-market asset class; Polymarket assigns a 60% chance of valuation above $1.8 trillion.ChatGPT’s reported one billion monthly users make distribution central as falling intelligence costs intensify the race for each user’s coordinating assistant.Trump’s voluntary 30-day review and DNA-screening debate leave governance unresolved while robotics and longevity attract sovereign-scale capital.
David Sinclair: GLP-1 Side Effect No One Talks About, AI in His Lab & Reversing Blindness | EP #251
Peter DiamandisDavid A. Sinclair
GLP-1s may deliver heart and brain benefits beyond weight loss, but Sinclair flags an unresolved blindness condition affecting roughly 20,000–30,000 U.S. cases annually.AI is accelerating molecule and cell analysis, while OSK and ER-100 remain preclinical; biotech investment still hinges on teams, cash, valuation, runway and clinical milestones.

