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Moonshots

Conversations about exponential technologies, AI, longevity, space, robotics, and the entrepreneurs attempting unusually large missions.

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160 EPISODESENTRACKED SHOW
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12 episodes2 active
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MoonshotsEN · 132 min

Anthropic Partners With SpaceX AI, Leopold's $5.5B Bet, and the Singularity Economy | EP #255

Peter DiamandisSalim IsmailDave BlundinDr. Alexander Wissner-Gross

Anthropic’s reported ARR from $9 billion at end-2025 to above $40 billion in May shifts the AI race from customer acquisition to compute supply.The Colossus 1 deal doubled Claude Code rate limits across 220,000 GPUs while Grok used about 11%, yet 1.6 million concurrent agents remain tiny versus billions of potential demand, keeping infrastructure bottlenecks and software-versus-hardware leadership in focus.

MoonshotsEN · 129 min

Google's Record Quarter, the White House Intervenes, and GPT 5.5 Silently Matches Mythos | EP 254

Peter DiamandisBrian ElliottSalim IsmailDave BlundinAlexander Wissner-Gross

Alphabet’s $109.9 billion quarter showed AI converting flat search volume into higher ad revenue, while Google Cloud grew 63% to $20 billion and vertical integration strengthened its position.Compute scarcity is shifting value toward chips, memory, energy and cooling, even as prerelease review, OpenAI’s monetization gap and enterprise deployment remain key risks to monitor.

MoonshotsEN · 27 min

David Sinclair: GLP-1 Side Effect No One Talks About, AI in His Lab & Reversing Blindness | EP #251

Peter DiamandisDavid A. Sinclair

GLP-1s may deliver heart and brain benefits beyond weight loss, but Sinclair flags an unresolved blindness condition affecting roughly 20,000–30,000 U.S. cases annually.AI is accelerating molecule and cell analysis, while OSK and ER-100 remain preclinical; biotech investment still hinges on teams, cash, valuation, runway and clinical milestones.

MoonshotsEN · 132 min

Elon Musk vs. Sam Altman, AI Job Loss, and OpenAI’s $852B Valuation | EP #247

Peter DiamandisSalim IsmailDave BlundinDr. Alexander Wissner-Gross

Anthropic drew $2 billion of secondary demand versus OpenAI’s $600 million, with pricing near $600 billion against OpenAI’s $852 billion raise.OpenAI retains 900 million users and enormous cash, while Anthropic’s managed agents target outcome-based enterprise spending. xAI’s rebuild after eight founding-engineer departures, alongside a predicted $2 trillion IPO, puts execution and model-scaling risks on watch.

MoonshotsEN · 131 min

Elon Enters the Chip Race, the S&P 500 Repricing, and Human Drivers Will Become Illegal | EP #242

Peter DiamandisSalim IsmailDave BlundinAlexander Wissner-Gross

Musk’s Terafab targets 1 terawatt of annual AI-compute capacity versus roughly 20 gigawatts today, making compute the proposed organizing resource of the economy.Demand may absorb every process node as autonomy, AI labor compression, and model distillation expand usage, but ASML, materials, power, labor, capital, and Musk’s timing remain critical execution risks.

MoonshotsEN · 33 min

AI Investor Panel: Where Smart Money Is Actually Going in AI | EP 219

Peter DiamandisAnjney MidhaBonnie ChanDave Blundin

AI deployment has already outgrown venture scale, with Peter Diamandis estimating $1 billion a day in U.S. deployment and potentially $3 billion a day by 2030.Strategic investors, public markets, credit and sovereign capital must join the funding effort as reasoning models generate roughly 10 times more tokens and electricity becomes the infrastructure constraint.Vertical applications offer lower-capital early-stage economics, while institutional access and political backlash remain key risks to monitor.

MoonshotsEN · 121 min

Meta’s 15 Billion Dollar AI Bet & The Race To ASI w/ Salim Ismail & Dave Blundin

Peter DiamandisAlexander Wissner-GrossDave Blundin

The AI race is becoming an energy race as China targets nuclear leadership by 2030 and produced roughly 700 GW of solar panels in 2024, while US licensing takes 10–12 years.Frontier models could become winner-take-all through self-improvement, while Cursor’s $500 million ARR and AI startup revenue demonstrate unusually capital-light economics; generation, distribution, storage, and regulation remain key constraints.

MoonshotsEN · 108 min

AI Is Making More Millionaires Than Anything in History w/ Salim Ismail & Dave Blundin | EP #181

Peter DiamandisSalim IsmailDave Blundin

AI-native startups are compressing the venture clock, with median time to $1 million in annual revenue falling from 16 months before 2020 to five months, and teams of 30–50 reaching multibillion-dollar scale.Compute, power and talent are becoming strategic bottlenecks, from xAI’s reported 340,000 Nvidia GPUs and planned one million to Meta’s $100 million packages, leaving infrastructure access and incumbent innovation traps as key risks to monitor.

MoonshotsEN · 51 min

Bitcoin’s Bull Run & the AI Arms Race: What You Need to Know w/ Salim Ismail | EP #166 [REUPLOAD]

Salim IsmailPeter Diamandis

China’s robotics surge is framed as a demographic necessity as its shrinking workforce drives automation, while drone delivery highlights how unevenly advanced infrastructure is already distributed.Gemini 2.5 may lead benchmarks, but OpenAI’s roughly $2.5 billion revenue versus Gemini’s sub-$500 million shows how usability and distribution can outweigh model leadership.AI investment is becoming frothy even as medicine, agent learning, and data-rich platforms expand the opportunity, leaving capital discipline and alignment as key risks to monitor.

MoonshotsEN · 52 min

Inside Magic Johnson’s Billion-Dollar Empire | EP #163

Peter DiamandisMagic Johnson

Magic Johnson turned overlooked urban demand into a repeatable investment thesis, using Magic Johnson Theatres’ top-10 performance to win 125 Starbucks stores across 40 markets and later applying the model to Burger King, real estate, and sports.His double bottom line pairs profit with jobs, supplier opportunities, and community impact, while disciplined exits and turnarounds at the Dodgers and Commanders show the operating mechanism; public-health access remains a personal and policy priority after 33 years managing HIV.